Perindopril Erbumine CAS 107133-36-8 Purity > 99.5% (HPLC) ACE Inhibitor API Hoobkas Zoo
Chaw tsim tshuaj paus Supply Perindopril Erbumine Related Intermediates
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Perindopril Erbumine CAS 107133-36-8
Tshuaj npe | Perindopril Erbumine |
Synonyms | Perindopril tert-Butylamine ntsev;Aceon;(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine ntsev |
CAS Nr | 107133-36-8 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C19H32N2O5.C4H11N |
Molecular Luj | 441.61 ib |
Melting Point | 126.0 ~ 128.0 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Kev txheeb xyuas | IR;HPLC |
Kev sib hloov tshwj xeeb [α]D20 | -66.0° ~ 69.0° |
Cov impurities A | ≤ 0.25% |
Cov impurities I | ≤0.10% |
Tsis paub impurities | ≤0.10% |
Cov impurities E | ≤ 0.40% |
Cov impurities B | ≤ 0.30% |
Cov impurities F | ≤ 0.20% |
Cov impurities H | ≤ 0.20% |
Tsis paub impurities | ≤0.10% |
Tag nrho cov impurities | <0.50% |
Cov ntsiab lus dej | ≤ 1.00% |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤ 20ppm |
Purity / Analysis Method | > 99.5% (HPLC) |
Yam khoom muaj feem | Ua raws li Specification |
Test Standard | Enterprise Standard |
Kev siv | API;ACE inhibitor;Antihypertensive |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Perindopril Erbumine (CAS: 107133-36-8), tseem hu ua Perindopril tert-Butylamine Salt, yog ib qho muaj zog ACE inhibitor uas yog siv los kho cov ntshav siab, plawv tsis ua hauj lwm lossis cov kab mob plawv.Inhibition ntawm cov enzyme no tiv thaiv kev tsim ntawm angiotensin II los ntawm angiotensin I, uas nyob rau hauv lem tiv thaiv vasoconstriction los ntawm angiotensin II.Perindopril Erbumine yog ib qho kev hais lus bioavailable ntev ua yeeb yam angiotensin converting enzyme (ACE) inhibitor (IC50 tus nqi ntawm 10 μM).Tshwj xeeb, Perindopril Erbumine yog ib qho tshuaj ntawm qhov ncauj ntawm Perindoprilat, lub zog ACE inhibitor nrog IC50 tus nqi ntawm 1.9 nM.