Pirfenidone CAS 53179-13-8 Purity ≥99.0% IPF
Supply Nrog High Purity, Commercial Production
Lub npe tshuaj: Pirfenidone
CAS: 53179-13-8 Nr
| Tshuaj npe | Pirfenidone |
| Synonyms | Perfenidone;5-Methyl-1-Phenylpyridine-2(1H)-ib;PFD;S-7701;AWM-69 |
| CAS Nr | 53179-13-8 |
| CAT Number | RF-API 108 |
| Tshuag xwm txheej | Hauv Tshuag |
| Molecular Formula | C12H11 Nr |
| Molecular Luj | 185.22 Nws |
| Melting Point | 96.0 txog 97.0 ℃ |
| Solubility | Soluble hauv DMSO |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau lub teeb daj Crystalline hmoov |
| Kev txheeb xyuas | IR |
| Purity | ≥99.0% |
| Poob rau ziab | ≤0.50% |
| Sulfated tshauv | ≤ 0.20% |
| Ib leeg Impurity | ≤0.50% |
| Tag nrho cov impurities | ≤ 1.0% |
| Hnyav Hlau | ≤ 20ppm |
| Test Standard | Enterprise Standard |
| Kev siv | API, Idiopathic Pulmonary Fibrosis (IPF) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Pirfenidone (CAS: 53179-13-8) yog nyob rau hauv ib pawg tshuaj hu ua antifibrotic agents.Pirfenidone tau qhia txog kev ua haujlwm hauv ntau yam mob fibrotic, suav nrog cov ntsws, lub raum thiab daim siab.Nws cuam tshuam rau koj lub cev tiv thaiv kab mob thiab txo cov fibrosis (scarring) hauv lub ntsws.Pirfenidone yog ib qho ntawm ob cov tshuaj uas tau pom zoo hauv Canada los kho Idiopathic Pulmonary Fibrosis (IPF).Pirfenidone yog ib qho inhibitor rau TGF-β ntau lawm thiab TGF-β stimulated collagen ntau lawm, txo zus tau tej cov TNF-α thiab IL-1β, thiab kuj muaj anti-fibrotic thiab anti-inflammatory zog.Nws tau pom zoo thawj zaug hauv Nyij Pooj rau kev kho mob ntawm cov neeg mob idiopathic pulmonary fibrosis tom qab kev sim tshuaj, raws li kev lag luam npe ntawm Pirespa los ntawm Shionogi, xyoo 2008. Nws tau pom zoo siv hauv European Union hauv 2011, hauv Canada hauv 2012, thiab hauv Tebchaws Meskas thaum Lub Kaum Hli 2014.
