Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Muab Vonoprasan Fumarate thiab Lwm Yam Nruab Nrab
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Tshuaj npe | Pyridine-3-Sulfonyl Chloride |
| Synonyms | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
| CAS Nr | 16133-25-8 |
| CAT Number | Qauv TSIS MUAJ: RF-PI540 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C5H4ClNO2S |
| Molecular Luj | 177.61 Nws |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Xim tsis muaj xim lossis daj daj daj |
| Purity / Analysis Method | ≥98.5% (GC) |
| Boiling Point | 110.0 ~ 112.0 ℃ / 2 hli Hg |
| Ib leeg Impurity | ≤0.50% |
| Tag nrho cov impurities | ≤ 1.5% |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate ntawm Vonoprasan Fumarate (CAS: 1260141-27-2) |
Pob: Lub raj mis, 25kg / chim, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) yog ib qho nruab nrab ntawm Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, nrhiav tau thiab tsim los ntawm Takeda thiab Otsuka, tau pom zoo los ntawm PMDA ntawm Nyiv thaum Lub Kaum Ob Hlis 2014, thiab tau qhia rau kev kho mob plab hnyuv, duodenal ulcer thiab reflux esophagitis.Vonoprazan fumarate muaj cov txheej txheem tshiab ntawm kev ua hu ua potassium-competitive acid blockers, uas muaj kev sib tw tiv thaiv kev khi ntawm cov poov tshuaj ions rau H +, K +-ATPase (tseem hu ua lub twj tso kua mis proton) hauv cov kauj ruam kawg ntawm gastric acid secretion hauv parietal hlwb.Vonoprazan tsis inhibit Na +, K +-ATPase kev ua haujlwm txawm tias nyob rau hauv ntau dua 500 npaug siab dua li ntawm lawv cov txiaj ntsig IC50 tawm tsam plab H +, K +-ATPase kev ua haujlwm.Tsis tas li ntawd, cov tshuaj tsis cuam tshuam los ntawm lub plab zais zis, tsis zoo li PPIs.
