(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0 ~ 102.0% (HPLC) Hoobkas

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Lub npe tshuaj: (R)-Lansoprazole

Lub ntsiab lus: Dexlansoprazole

CAS: 138530-94-6 Nr

Kev ntsuam xyuas: 98.0 ~ 102.0% (HPLC, % w / w)

Cov tsos mob: Dawb rau Off-White Crystalline Hmoov

E-Mail: alvin@ruifuchem.com

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Product Detail

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Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Lansoprazole Intermediates
Lansoprazole CAS 103577-45-3
Lansoprazole Chloride Compound CAS 127337-60-4
(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6

Chemical Properties:

Tshuaj npe	(R) - Lansoprazole
Synonyms	R-(+)-Lansoprazole;Dexlansoprazole;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;T 168390;TSI 390;Lansoprazole Impurity 14;Dexlansoprazole Lwm yam impurities 2;(R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-Benzimidazole;
CAS Nr	138530-94-6
CAT Number	RF-PI 1916
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C16H14F3N3O2S
Molecular Luj	369.36 ib
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystalline Hmoov
Solubility	Soluble hauv Dimethylformamide, Yuav luag Insoluble hauv dej
Clarity & Colour of Solution	Ua tau raws li qhov yuav tsum tau ua
Identification IR	Infrared absorption spectrum yuav tsum ua raws li cov khoom siv
Kev txheeb xyuas HPLC	Lub sijhawm khaws cia ntawm lub ncov tseem ceeb yuav tsum ua raws li qhov kev siv
Kev sib hloov tshwj xeeb	+142.0° ~ + 149.0°
Melting Point	~ 140.0 ℃
Cov ntsiab lus dej (KF)	<1.00%
Residue ntawm Ignition	<0.10%
Related Impurities	(HPLC)
Nitrogen Oxides	<0.10%
Sulfone	<0.40%
Sulfide	<0.20%
Lwm Yam Ib Leeg Impurity	<0.10%
Tag nrho cov impurities	<0.60%
Optical Purity (HPLC)	> 99.5%
Assay	98.0 ~ 102.0% (HPLC, % w / w, raws li tsis muaj dej, hnyav-dawb)
Hnyav Hlau	<10ppm
Residual Solvents
Toluene	<890ppm
n-Heptane	<5000ppm
Cov kab mob endotoxin	<2.5EU/mg
Test Standard	USP Txuj;Suav Pharmacopoeia
Kev siv	API;Lub Orally Active Proton Pump Inhibitor

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

(R)-Lansoprazole (CAS: 138530-94-6) yog R enantiomer ntawm Lansoprazole, Lansoprazole (AG 1749) yog cov tshuaj tiv thaiv qhov ncauj proton twj tso kua mis uas tiv thaiv lub plab los ntawm kev tsim cov kua qaub.Dexlansoprazole rau Lansoprazole dextroisomer, yog ib hom tshuaj tiv thaiv kab mob peptic rau kev hloov benzimidazole derivatives, nyob rau hauv cov qauv molecular rau hauv lub caij fluorine, thib ob proton twj tso kua mis inhibitors omeprazole tom qab.Dexlansoprazole muaj cov nyhuv ntawm inhibiting lub secretion ntawm gastric acid, cov nyhuv yog zoo dua li ntawm lwm yam tshuaj (Omeprazole, Pantoprazole, Rebela, Tetrazolium) muaj peev xwm ho inhibit qhov tshwm sim ntawm rwj.Nws yog superior rau famotidine los yog Omeprazole rau kev puas tsuaj ntawm cawv induced gastric mucosa thiab duodenal rwj feem ntau tshwm sim los ntawm acid hypersecretion.Tsis tas li ntawd, cov khoom lag luam muaj cov nyhuv tib yam los tiv thaiv Helicobacter pylori raws li kev npaj bismuth, thiab siv rau reflux esophagitis thiab Zhuo AI syndrome.Takeda Pharmaceuticals tau txais kev pom zoo ntawm dexlansoprazole, ib qho kev tso tawm dual ntawm (R)-isomer ntawm lansoprazol proton twj tso kua mis inhibitor (PPI) twb nyob rau hauv khw, los ntawm FDA nyob rau lub ib hlis ntuj 2009. Dexlansoprazole yog ib tug ncua sij hawm tso tshuaj ntsiav rau ib zaug ib hnub, kho qhov ncauj. Kev kub ntxhov cuam tshuam nrog cov tsos mob uas tsis yog-erosive gastroesophageal reflux tus kab mob (GERD), kho cov kab mob erosive esophagitis (EE) thiab kev saib xyuas kho EE.