Ramelteon Acrylonitrile CAS 196597-79-2 Ramelteon Intermediate Purity > 98.0% (HPLC)
Cov Chaw Tsim Khoom Ua Lag Luam thiab Chaw Muag Khoom, Intermediates ntawm Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
Tshuaj npe | (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)acetonitrile |
Synonyms | Ramelteon Acrylonitrile;Ramelteon Impurity 6;Ramelteon Impurity B;Ramelteon Cyano Impurity;(E)-2-(6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-ylidene)acetonitrile;(2E)-2-(1,2,6,7-Tetrahydrocyclopenta[e][1]benzofuran-8-ylidene)acetonitrile;(1,2,6,7-Tetrahydro-3-oxa-as-indacen-8-ylidene)-acetonitrile |
CAS Nr | 196597-79-2 |
CAT Number | TIAB SA 2886 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C13H11 Nr |
Molecular Luj | 197.23 Nws |
Melting Point | 146.0 ~ 151.0 ℃ |
Boiling Point | 392.1 ± 21.0 ℃ ntawm 760 mmHg |
Flash Point | 165.0 ± 15.9 ℃ |
Qhov ntom | 1.321 ± 0.06 g / cm3 |
HS Code | 2932999099 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau daj hmoov hmoov |
Purity / Analysis Method | > 98.0% (HPLC) |
Poob rau ziab | <1.00% |
Tag nrho cov impurities | <2.00% |
1 H NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Ramelteon (CAS: 196597-26-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
(E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)acetonitrile (CAS: 935-56-8) yog ib qho nruab nrab ntawm Ramelteon (CAS: 196597) -26-9).Ramelteon (TAK-375) yog ib qho tshiab melatonin receptor agonist rau tib neeg MT1 thiab MT2 receptors thiab nqaij qaib forebrain melatonin receptors nrog Ki ntawm 14 pM, 112 pM thiab 23.1 pM, feem.Lub melatonin molecule tau hloov pauv feem ntau los ntawm kev hloov cov nitrogen ntawm lub nplhaib indole nrog cov pa roj carbon monoxide kom muab lub nplhaib indane thiab los ntawm kev sib xyaw 5-methoxyl pawg hauv lub nplhaib indole rau hauv lub nplhaib furan nruj dua.Kev xaiv ntawm qhov tshwm sim ramelteon rau MT1 receptor iseight lub sij hawm ntau dua li ntawm MT2 receptor.Tsis zoo li melatonin, nws muaj txiaj ntsig zoo hauv kev pib pw tsaug zog (MT1 kev ua si) dua li hloov kho lub circadian atherosclerosis (MT2 kev ua si).Nws pom tau tias muaj txiaj ntsig zoo dua li melatonin tab sis tsis muaj txiaj ntsig zoo dua li benzodiazepines raws li hypnotic.Qhov tseem ceeb, cov tshuaj no tsis muaj kev lav phib xaub (nws tsis yog cov tshuaj tswj hwm).Yog li ntawd, nws tsis ntev los no tau pom zoo rau kev kho mob ntawm insomnia.