Ramelteon (TAK-375) CAS 196597-26-9 Purity > 99.5% (HPLC)
Cov Chaw Tsim Khoom Ua Lag Luam thiab Chaw Muag Khoom, Intermediates ntawm Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Tshuaj npe | Ramelteon |
| Synonyms | (S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethyl]propionamide;TAK-375;TSI 375;TSI 375;Rozerem |
| CAS Nr | 196597-26-9 |
| CAT Number | TIAB SA 2885 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C16H21NO2 |
| Molecular Luj | 259.35 Nws |
| Melting Point | 113.0 txog 116.0 ℃ |
| Boiling Point | 455.3 ± 24.0 ℃ |
| Qhov ntom | 1.119 ± 0.06 g / cm3 |
| Kev sib hloov tshwj xeeb [α]20/D | -55.0 ° rau -60.0 ° (C = 1, CHCL3) |
| Solubility hauv dej | Insoluble hauv dej (11 mg / l 25 ℃) |
| Solubility | Soluble hauv Ethanol, Methanol, DMSO |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb Crystalline hmoov |
| Purity / Analysis Method | > 99.5% (HPLC) |
| Melting Point | 113.0 ~ 116.0 ℃ |
| Poob rau ziab | <0.50% |
| Residue ntawm Ignition | <0.10% |
| Isomer Purity | <0.10% |
| Hnyav Hlau | <10ppm |
| Acidity los yog Alkalinity | Ua raws |
| Ethanol | <5000ppm |
| Ib leeg Impurity | <0.20% |
| Tag nrho cov impurities | <0.50% |
| Infrared Spectrum | Raws li tus qauv |
| Test Standard | Enterprise Standard |
| Kev siv | API, Pom zoo rau Kev Kho Mob Insomnia |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Ramelteon (CAS: 196597-26-9) yog thawj zaug pom zoo los ntawm US Food and Drug Administration (FDA) thaum Lub Xya Hli 22, 2005, tom qab ntawv pom zoo los ntawm Pharmaceuticals thiab Medical Devices Agency (PMDA) thaum Lub Plaub Hlis 16, 2010. Nws tau tsim thiab ua lag luam raws li Rozerem® los ntawm Takeda,tuaj yeem siv los kho insomnia nrog nyuaj pw tsaug zog, thiab muaj cov txiaj ntsig zoo rau kev pw tsaug zog ntev thiab luv luv insomnia.Cov khoom no tuaj yeem xaiv qhib hom 1 thiab hom 2 receptors ntawm melatonin (MT1, MT2), ua kom qeeb yoj pw tsaug zog (SWS) thiab qhov muag nrawm nrawm (REW), yog li txo qis insomnia.Ramelteamide yog thawj zaug uas tsis muaj kev quav tshuaj insomnia kho uas tsis nyob hauv kev tswj hwm tshwj xeeb.Cov khoom no yog melatonin receptor agonist.Nws muaj kev sib raug zoo nrog cov melatonin MT1 thiab MT2 receptors, thiab muaj qhov tshwj xeeb thiab ua tiav cov nyhuv ntawm MT1 thiab MT2 receptors, tab sis tsis cuam tshuam nrog MT3 receptors.Tsis tas li ntawd, nws tsis khi rau cov neurotransmitter receptors xws li GABA receptor complexes, thiab tsis cuam tshuam nrog kev ua haujlwm ntawm cov enzymes feem ntau nyob rau hauv ib qho chaw.Yog li, nws tuaj yeem zam qhov cuam tshuam nrog GABA tshuaj (uas yuav ua rau muaj tsheb sib tsoo, ntog thiab pob txha).Etc.) thiab kev quav yeeb tshuaj thiab kev vam khom.Rozerem® muaj nyob rau hauv cov ntsiav tshuaj-coated zaj duab xis rau kev siv qhov ncauj, muaj 8 mg ntawm Ramelteon dawb.Cov neeg laus pom zoo koob tshuaj yog 8 mg noj nyob rau hauv 30 feeb tom qab mus pw.
-
Ramelteon (TAK-375) CAS 196597-26-9 Purity >99....
-
2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Hauv ...
-
Despropionyl Ramelteon Hydrochloride CAS 196597 ...
-
Ramelteon Acrylonitrile CAS 196597-79-2 Ramelte...
-
Ramelteon Intermediate 12 CAS 1053239-39-6 Puri ...
-
Ramelteon Intermediate CAS 196597-78-1 Purity >...