Ramelteon Intermediate CAS 196597-78-1 Purity > 98.5% (HPLC)
Cov Chaw Tsim Khoom Ua Lag Luam thiab Chaw Muag Khoom, Intermediates ntawm Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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Tshuaj npe | 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-ib |
Synonyms | 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-ib;Ramelteon Intermediate 1;Ramelteon I |
impurity | Ramelteon Impurity A |
CAS Nr | 196597-78-1 |
CAT Number | TIAB SA 2883 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 20 Tons ib Hlis |
Molecular Formula | C11H10O2 |
Molecular Luj | 174.20 Nws |
Melting Point | 133.0 txog 137.0 ℃ |
Boiling Point | 334.2 ± 42.0 ℃ |
Qhov ntom | 1.288 ± 0.06 g / cm3 |
Hazard Class | Irritant |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Pale Yellow Solid Powder |
Purity / Analysis Method | > 98.5% (HPLC) |
Melting Point | 133.0 txog 137.0 ℃ |
Dej (los ntawm Karl Fischer) | <0.50% |
Residue ntawm Ignition | <0.10% |
Tag nrho cov impurities | <1.50% |
1 H NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Ramelteon (CAS: 196597-26-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
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Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one (CAS: 196597-78-1) yog siv los ua tus nruab nrab ntawm Ramelteon (CAS: 196597-26-9) , niam nucleus ntawm synthesizing Ramelteon.Ramelteon yog thawj zaug hauv chav kawm tshiab ntawm cov neeg pw tsaug zog uas xaiv khi rau MT1 thiab MT2 receptors hauv suprachiasmatic nucleus (SCN), es tsis txhob khi rau GABA receptors.Ramelteon tsis pom muaj kev cuam tshuam zoo rau GABAA receptors, uas cuam tshuam nrog anxiolytic, myorelaxant, thiab amnesic teebmeem.Ramelteon tuaj yeem siv rau insomnia, tshwj xeeb tshaj yog qeeb pw tsaug zog pib.Ramelteon tsis tau pom tias yuav tsim kev vam khom thiab tsis muaj peev xwm ua rau muaj kev tsim txom, thiab kev tshem tawm thiab rov qab pw tsaug zog uas yog ib txwm nrog GABA modulators tsis nyob hauv ramelteon.Qee cov kws kho mob kuj tseem siv ramelteon rau kev kho mob qeeb pw tsaug zog theem syndrome.Kho insomnia (teeb meem pw tsaug zog).Nws kuj tseem siv tau rau lwm yam mob raws li koj tus kws kho mob txiav txim siab.Ramelteon yog ib tug melatonin agonist.Nws ua haujlwm los ntawm kev ua haujlwm ntawm melatonin receptors hauv lub hlwb, uas pab koj tsaug zog.