Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
Chaw tsim tshuaj paus kev lag luam muab Remdesivir thiab cuam tshuam nrog cov khoom zoo
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Tshuaj npe | N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester |
Synonyms | Remdesivir Intermediate;Remdesivir Side Chain;Remdesivir p-NitroPhenoxy L-Alanine impurity;Remdesivir Impurity 4;Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate |
CAS Nr | 1354823-36-1 |
CAT Number | Qauv TSIS MUAJ: RF-PI297 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C21H27N2O7P |
Molecular Luj | 450.42 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Yuav luag Dawb Hmoov |
Kev txheeb xyuas | IR, HPLC |
Poob rau ziab | ≤ 1.0% |
Ib leeg Impurity | ≤0.50% |
Hnyav Hlau | ≤ 20ppm |
Purity | ≥98.0% |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Remdesivir (CAS 1809249-37-3);COVID 19 |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, tseem hu ua Remdesivir Impurity 4) yog phosphoramidate sidechain feem ntau siv rau kev npaj ntawm Remdesivir (CAS) 1809249-37-3, GS-5734), uas yog cov tshuaj tshiab tshuaj tiv thaiv kab mob tshawb nrhiav keeb kwm yav dhau los rau kev kho tus kab mob Ebola tus kab mob thiab kab mob Marburg thiab tom qab ntawd kuj tau pom tias muaj kev tiv thaiv kab mob tiv thaiv kab mob coronaviruses (xws li SARS-Cov-2/ Covid 19).Thaum muaj tus kab mob Coronavirus tshiab 2019 (COVID-19), Remdesivir (CAS 1809249-37-3) yog ib qho ntawm cov khoom siv tshawb fawb txog COVID-19.Remdesivir, muag raws li lub npe lag luam Veklury, yog cov tshuaj tiv thaiv kab mob dav dav tsim los ntawm lub tuam txhab biopharmaceutical Gilead Sciences.Nws yog siv los ntawm kev txhaj tshuaj rau hauv cov hlab ntsha.Thaum muaj tus kab mob COVID-19 kis thoob qhov txhia chaw, Remdesivir tau pom zoo los yog tso cai siv thaum muaj xwm ceev los kho COVID-19 nyob ib ncig ntawm 50 lub teb chaws.Hloov kho cov lus qhia los ntawm Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Hauv Ntiaj Teb thaum Lub Kaum Ib Hlis 2020 suav nrog cov lus pom zoo rau kev siv Remdesivir rau kev kho mob ntawm COVID-19.