Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
Chaw tsim tshuaj paus kev lag luam muab Remdesivir thiab cuam tshuam nrog cov khoom zoo
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Tom ntej: Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Intermediate CAS 1191237-80-5
Tom ntej: 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1
Tshuaj npe | 2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl)-L-alaninate |
Synonyms | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir Impurity 21 |
CAS Nr | 1911578-98-7 |
CAT Number | Qauv Zauv: RF-PI303 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C21H27N2O7P |
Molecular Luj | 495.38 ib |
Qhov ntom | 1.2g / cm3 |
Melting Point | 92.0 ~ 96.0 ℃ (lit.) |
Boiling Point | 356.7 ℃ ntawm 760 mmHg |
Shipping Condition | Shipped nyob rau hauv ambient kub |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Infrared Spectrum | Raws li tus qauv |
Purity | ≥99.0% |
Poob rau ziab | ≤0.50% |
Ib leeg Impurity | ≤0.50% |
Tag nrho cov impurities | ≤ 1.0% |
Hnyav Hlau | ≤ 20ppm |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Remdesivir (CAS 1809249-37-3) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) yog ib qho tseem ceeb nruab nrab hauv kev npaj ntawm Remdesivir ntsig txog analogs.Remdesivir yog ib qho monophosphoramidate prodrug ntawm adenosine analog, yog ib qho kev tshawb nrhiav dav-spectrum antiviral agent nrog hauv vitro ua haujlwm tiv thaiv SARS tus kabmob coronavirus, MERS tus kabmob coronavirus thiab, tsis ntev los no, Covid-19.Remdesivir feem ntau yog tsim los ua kev kho mob rau cov kab mob filovirus xws li Ebola virus kab mob lossis Marburg tus kab mob.Tom qab ntawd, Remdesivir tau pom tias muaj cov tshuaj tiv thaiv kab mob tiv thaiv lwm cov kab mob RNA ib leeg xws li cov kab mob ua pa syncytial, Nipah virus, Hendra virus, Junin virus, Lassa fever virus thiab cov kab mob coronaviruses (xws li MERS thiab SARS virus).Tsis ntev los no nws tau raug kawm los ua cov tshuaj cog lus rau kev kho mob ntawm COVID-19 (tus kab mob SARS tshiab).Remdesivir, tsim los ntawm Gilead Sciences, yog ib qho adenosine prodrug uas metabolizes rau hauv nws daim ntawv nquag GS-441524 uas cuam tshuam nrog kev ua ntawm tus kab mob RNA-dependent RNA polymerase thiab evades proofreading los ntawm viral exoribonuclease (ExoN), ua rau txo qis hauv cov kab mob RNA ntau lawm.