Rifamycin S CAS 13553-79-2 Purity > 97.5% (HPLC) Hoobkas
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Tshuaj npe | Rifamycin S |
Synonyms | 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin;Rifaximin EP Impurity E |
CAS Nr | 13553-79-2 |
CAT Number | Qauv TSIS MUAJ: RF-PI2058 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 500MT / Xyoo |
Molecular Formula | C37H45NO12 |
Molecular Luj | 695.76 ib |
rhiab heev | Thaum tshav kub kub Sensitive |
Kev sib hloov tshwj xeeb [α]20/D | +451.0° ~ + 500.0° (C = 0.1 in MeOH) |
Melting Point | 201 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Yellow lossis txiv kab ntxwv Yellow Crystalline hmoov |
Poob rau ziab | ≤3.00% (4h 100 ℃) |
Residue ntawm Ignition | ≤0.50% |
Yam khoom muaj feem | |
Rifamycin-O | ≤0.50% |
Rifamycin-B | ≤0.50% |
Ib Peak | ≤ 1.00% |
Tag nrho cov impurities | ≤ 2.50% |
Purity / Analysis Method | > 97.5% (HPLC) |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Txee lub neej | 24 lub hlis txij hnub tsim khoom yog tias khaws cia kom raug |
Kev siv | Ib qho tseem ceeb Intermediate rau Synthesis ntawm Rifamycin Tshuaj |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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Rifamycin S (CAS: 13553-79-2) yog ib qho tseem ceeb nruab nrab rau kev sib txuas ntawm cov tshuaj rifamycin.Rifamycin S yog ib qho tshuaj tua kab mob semi-synthetic.Rifamycin S yog quinone thiab tshuaj tua kab mob tiv thaiv kab mob Gram-positive (xws li MRSA).Rifamycin S yog oxidized cov ntaub ntawv ntawm ib tug reversible oxidation-txo system uas muaj ob electrons.Rifamycin S generates reactive oxygen hom (ROS) thiab inhibits microsomal lipid peroxidation.Rifamycin S tuaj yeem siv rau kev mob ntsws thiab mob ruas.Cov rifamycins yog ib pawg ntawm cov tshuaj muaj feem xyuam rau cov tshuaj tua kab mob uas tau txais los ntawm fermentation los ntawm kab lis kev cai ntawm Streptomycesmediterranei.Lawv nyob rau hauv chav kawm ntawm cov tshuaj tua kab mob hu ua theansamycins uas muaj lub nplhaib macrocyclic txuas hla ob txoj haujlwm tsis nyob ib sab ntawm ib qho tshuaj tsw qab.Cov rifamycins thiab ntau ntawm lawv cov semisynthetic derivativeshave muaj ib tug dav spectrum ntawm antimicrobial kev ua ub no.Lawv yog cov tseem ceeb tshaj plaws tiv thaiv kab mob Gram-positive thiab M. tuberculosis.Txawm li cas los xij, lawv kuj tseem muaj zog tiv thaiv kab mob Gram-tsis zoo thiab ntau yam kab mob.Rifampin, asmisynthetic derivative ntawm Rifamycin B, raug tso tawm raws li tus neeg sawv cev anantitubercular nyob rau hauv lub tebchaws United States nyob rau hauv 1971. Ib tug secondsemisynthetic derivative, rifabutin, tau pom zoo nyob rau hauv 1992 rau kev kho mob ntawm atypical mycobacterial kab mob.
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