Roflumilast CAS 162401-32-3 Assay 99.0 ~ 101.0% API

Lus piav qhia luv luv:

Lub npe tshuaj: Roflumilast

CAS: 162401-32-3 Nr

Kev ntsuam xyuas: 99.0 ~ 101.0% (Xam ntawm Kev Qhuab Qhia)

Cov tsos mob: Dawb los yog yuav luag dawb crystalline hmoov

API PDE-4 Inhibitor COPD

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
Tom ntej: 4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Chemical Properties:

Tshuaj npe	Roflumilast
Synonyms	3-(Cyclopropylmethoxy)-N-(3,5-Dichloropyridin-4-yl)-4-(Ddifluoromethoxy)benzamide
CAS Nr	162401-32-3
CAT Number	Qauv TSIS MUAJ: RF-PI2075
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C17H14Cl2F2N2O3
Molecular Luj	403.21 Nws
Qhov ntom	1.471 ± 0.060 g / cm3
rhiab heev	Thaum tshav kub kub Sensitive
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb los yog Yuav luag Dawb Crystalline Hmoov
Solubility	Dawb soluble nyob rau hauv acetone, sparingly soluble nyob rau hauv acetronitrile, me ntsis insoluble nyob rau hauv anhydrous ethanol, xyaum insoluble nyob rau hauv dej
Melting Point	157.0 ~ 162.0 ℃
Poob rau ziab	<0.50%
Residue ntawm Ignition	≤0.10%
Hnyav Hlau	≤10ppm
Chloride	≤ 0.01%
Identification A. UV	Lub wavelength ntawm qhov siab tshaj plaws nqus yuav tsum yog 213 ~ 251nm
Identification B. IR	IR absorption spectrum ntawm cov qauv sib raug rau qhov kev siv ib qho
Kev txheeb xyuas C.	Nws qhia txog cov tshuaj Fluoride
Yam khoom muaj feem
Ib leeg Impurity	≤0.10%
Tag nrho cov impurities	<0.50%
Residual Solvents
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Assay	99.0 ~ 101.0% (Xaiv ntawm Kev Qhuav Qhuav)
Test Standard	Enterprise Standard
Kev siv	API;COPD

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

Roflumilast (CAS: 162401-32-3) yog ib qho kev xaiv qhov ncauj phosphodiesterase-4 (PDE-4) inhibitor thiab benzamide compound.Nws tau tsim los ntawm German tuam txhab Altana hauv xyoo 1993 thiab yog tib lub qhov ncauj PDE-4 inhibitor siv los kho cov kab mob ua pa uas pom zoo rau kev muag khoom.Roflumilast yog thawj cov tshuaj ntawm nws cov hom phiaj rau cov mob hnyav mob ntsws obstructive pulmonary (COPD), thiab nws kuj yog thawj cov tshuaj tiv thaiv kab mob hauv qhov ncauj tshwj xeeb tsim rau cov neeg mob COPD.Nws cov khoom tshwj xeeb tuaj yeem pab tswj COPD: thaum siv ua ke nrog cov tshuaj bronchodilators los kho cov neeg mob COPD hnyav heev, Roflumilast tuaj yeem muaj qhov zoo ntawm kev txo cov tsos mob thiab kev tsis zoo, yog li ua rau nws yog thawj cov tshuaj uas tsom rau cov neeg mob rov qab deteriorating phenotype-spAecific COPD. thiab huab cua loj heev cuam tshuam cuam tshuam nrog hnoos ntev thiab ntau phlegm.Dhau li ntawm kev kho mob COPD hnyav, Roflumilast tseem tuaj yeem siv los tiv thaiv thiab kho tsiaj cov kab mob ua pa, ua pa ntau dhau ntawm cov hnoos qeev, mob ntsws asthmatic, thiab mob ntsws bronchitis thiab huab cua sacculitis nrog rau kev ua pa txawv txav.