Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5% ~ 102.0% API Hoobkas High Purity
Muab khoom nrog High Purity thiab ruaj khov zoo
Rosuvastatin Calcium
CAS: 147098-20-2 Nr
Kev tsim khoom lag luam
Tshuaj npe | Rosuvastatin Calcium |
Synonyms | ZD 4522 Calcium;(E)-6-[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate;(6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl (methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
CAS Nr | 147098-20-2 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C44H54CaF2N6O12S2 |
Molecular Luj | 1001.14 |
Melting Point | 122 ℃ |
Shipping Condition | Shipped nyob rau hauv ambient kub |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Kev sib hloov tshwj xeeb | +17.0° ~ +21.0°° |
Kev txheeb xyuas | A. Ua tau raws li qhov yuav tsum tau ua B. UV: λmax = 243nm C. IR: Zoo ib yam li Reference Substance D. X-Ray: Zoo ib yam li Cov Khoom Siv |
Chloride | ≤0.10% |
Sulfate | ≤0.10% |
Enantiomer | ≤ 0.15% |
Calcium Cov ntsiab lus | 3.5% ~ 4.5% |
Yam khoom muaj feem | |
Diastereomer | ≤ 0.15% |
5-Oxo-Rosucastatin | ≤ 0.15% |
Duab Degradation 1 | ≤ 0.15% |
Duab Degradation 2 | ≤ 0.15% |
Rosuvastatin Lactone | ≤ 0.15% |
Rosuvastatin Methyl Ester | ≤ 0.15% |
Rosuvastatin Isoamyl Ester | ≤ 0.15% |
Tej yam tsis paub impurity | ≤0.10% |
Tag nrho cov impurities | ≤ 0.75% |
Moisture (KF) | ≤ 3.0% |
Hnyav Hlau | ≤ 20ppm |
Isoamyl Bromide yog ib qho khoom noj khoom haus | ≤ 37.5ppm |
Residual Solvents | |
Ethyl Ether | ≤300ppm |
Cov tshuaj acetonitrile | ≤410ppm |
Isoamyl cawv | ≤5000ppm |
DMF | ≤880ppm |
Assay | 98.5% ~ 102.0% (caculated ntawm lub hauv paus anhydrous) |
Test Standard | Enterprise Standard;BP / USP / EP Txuj |
Kev siv | API |
Pob: Lub raj mis, chim, Cardboard nruas, 25kg / chim, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo
Rosuvastatin Calcium (CAS: 147098-20-2) yog cov tshuaj tiv thaiv hyperlipidemia uas belongs rau inhibitor ntawm HMG-CoA reductase ua tiav los ntawm British AstraZeneca tuam txhab.Nws yog qhov tsim nyog rau kev kho mob ntawm ntau yam lipid txawv txav, suav nrog hypercholesterolemia, sib xyaw lipid zoo txawv txav thiab yooj yim hypertriglyceridemia.Rosuvastatin Calcium (CAS: 147098-20-2) yog teev raws li cov tshuaj muaj zog tshaj plaws thiab cov tshuaj statins uas tau nkag mus rau hauv kev ua lag luam rau lipid-txo thiab hloov kho.Piv nrog rau atorvastatin uas tam sim no lees paub nrog lub ntiaj teb cov txiaj ntsig zoo tshaj plaws, nws muaj txiaj ntsig zoo ntawm kev txo qis LDL cov roj cholesterol thiab nce qib ntawm cov lipoprotein siab.Ntxiv mus, nws muaj kev kam rau siab zoo dua, txo cov kev mob tshwm sim thiab cov yam ntxwv ntawm pharmacokinetic nrog rau ib nrab-lub neej txog 20h.