(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Intermediate Purity > 99.0% (GC)

Lus piav qhia luv luv:

Lub npe tshuaj: (S)-1-Boc-3-Hydroxypiperidine

CAS: 143900-44-1 Nr

Chiral Purity:> 99.0% (GC)

Tshuaj Purity:> 99.0% (GC)

Cov tsos mob: Dawb hmoov los yog Crystals

Intermediate of Ibrutinib (CAS: 936563-96-1)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Chemical Properties:

Tshuaj npe	(S)-1-Boc-3-Hydroxypiperidine
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-Hydroxypiperidine;(S)-1-Boc-3-Piperidinol
CAS Nr	143900-44-1, ib
CAT Number	Qauv TSIS MUAJ: RF-CC299
Tshuag xwm txheej	Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 20 Tons / Lub Hlis
Molecular Formula	C10H19NO3
Molecular Luj	201.27 Nws
Melting Point	52.0 ~ 56.0 ℃
Solubility	Soluble hauv Methanol
Kev sib hloov tshwj xeeb [a]20/D	+9.0° ~ + 11.0° (C = 1 in Chloroform)
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb hmoov los yog Crystals
Chiral Purity	> 99.5% (GC)
Tshuaj Purity	> 99.5% (GC)
Dej (KF)	≤0.50%
Methanol (GC)	≤ 50ppm
Ethanol (GC)	≤ 50ppm
DCM (GC)	≤ 500ppm
3-Hydroxypiperidine	≤0.10%
3-Hydroxypyridine	≤ 0.20%
1-Boc-3-Piperidone	≤0.10%
1-Boc-4-Hydroxypiperidine	≤0.10%
1.96 TSI	≤ 0.20%
Tej yam tsis meej tsis meej	≤0.10%
Test Standard	Enterprise Standard
Kev siv	Pharmaceutical Intermediates;Chiral Compounds

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.

Qhov zoo:

FAQ:

Daim ntawv thov:

(S)-1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) yog ib qho tseem ceeb chiral intermediate rau cov synthesis ntawm Ibrutinib (CAS: 936563-96-1).Ibrutinib yog ib hom Bruton tyrosine kinase (BTK) inhibitor, nws tuaj yeem siv rau kev kho mob ntawm cov qog ntshav qog ntshav qog ntshav (CLL) thiab mantle cell lymphoma (MCL).MCL thiab CLL yog koom nrog B-cell non-Hodgkin's lymphoma, uas nyuaj rau kho thiab yooj yim rau rov tshwm sim.Hom tshuaj tiv thaiv kab mob tsis muaj lub hom phiaj, feem ntau tshwm sim 3 lossis 4 qhov tsis zoo tshwm sim.Ibrutinib thiab B lymphocytes tuaj yeem tsom nrog BTK uas yog qhov tsim nyog rau kev tsim, sib txawv, thiab xa cov ntaub ntawv, inhibit BTK kev ua haujlwm tsis zoo, thiab inhibit qog cell proliferation thiab ciaj sia taus.Ibrutinib tuaj yeem nqus tau sai sai tom qab kev tswj hwm qhov ncauj, thaum lub sijhawm 1 ~ 2h mus txog qhov siab tshaj plaws ntawm cov ntshav, cov kev cuam tshuam tsis zoo rau ib lossis ob, yog li ntawd, Ibrutinib yuav dhau los ua kev xaiv tshiab ntawm kev kho mob CLL thiab MCL.