Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity > 99.0% (HPLC) API Hoobkas High Quality Featured duab

Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity > 99.0% (HPLC) API Hoobkas Zoo

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Lub npe tshuaj: Sitagliptin Phosphate Monohydrate

CAS: 654671-77-9 Nr

Purity:> 99.0% (HPLC ntawm lub hauv paus qhuav)

Cov tsos mob: Dawb rau Off-White Crystalline Hmoov

Rau kev kho mob ntawm hom II mob ntshav qab zib mellitus

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Nqe lus piav qhia:

Muab Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
Tom ntej: 2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Chemical Properties:

Tshuaj npe	Sitagliptin Phosphate Monohydrate
Synonyms	(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- (2,4,5-trifluorophenyl)butan-1-ib phosphate monohydrate
CAS Nr	654671-77-9
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C16H20F6N5O6P
Molecular Luj	523.3240802 ib
Melting Point	202.0 ~ 204.0 ℃
Dej Solubility	Soluble hauv dej
Kev sib hloov tshwj xeeb	-18.0° ~ 23.0° C = 1 dej
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystalline Hmoov
Kev txheeb xyuas los ntawm HPLC	Lub sijhawm khaws cia ntawm tus qauv yog concordant nrog cov qauv siv
IR-Infrared Spectrum	IR Absorption Spectrum ntawm tus qauv yuav tsum sib haum nrog cov qauv spectrum
Phosphate	Ua raws
Purity / Analysis Method	> 99.0% (HPLC ntawm lub hauv paus qhuav)
Cov ntsiab lus dej (KF)	3.3% ~ 4.4%
Residue ntawm Ignition	≤ 0.20%
Sulfate	≤ 0.02%
Chloride	≤ 0.05%
Chiral impurity	<0.50%
Yam khoom muaj feem
Ib leeg Impurity	<0.50%
Tag nrho cov impurities	<1.0%
Ethyl Acetate	<0.50%
Hnyav Hlau	<20 ppm
Test Standard	Enterprise Standard
Kev siv	Pharmaceutical Intermediates

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.

Qhov zoo:

FAQ:

Daim ntawv thov:

Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), tshuaj tshiab rau kev kho mob ntshav qab zib hom 2.Thaum Lub Yim Hli 2009, cov tshuaj tau pom zoo los ntawm European Union ua cov tshuaj thawj zaug rau kev kho mob ntshav qab zib hom 2.Sitagliptin Phosphate yog thawj FDA-pom zoo dipeptidyl peptidase-IV inhibitor los siv rau hauv kev kho mob ntshav qab zib hom 2 nyob deb, raws li lub npe lag luam Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) sai thiab zoo degrades GLP-1, GLP-1, uas yog qhov zoo tshaj plaws stimulator ntawm insulin ntau lawm thiab secretion Yog li ntawd, inhibition ntawm DPP-IV tuaj yeem txhim kho lub luag haujlwm ntawm endogenous GLP-1, yog li ua kom cov ntshav nce ntxiv. qib insulin, yog li txo qis thiab tswj cov ntshav qabzib hauv cov neeg mob ntshav qab zib.Tam sim no, cov tshuaj tau lees paub tias DPP-IV inhibitor yog ib yam tshiab ntawm cov tshuaj tiv thaiv kab mob ntshav qab zib, thiab cov txiaj ntsig kev kho mob pom tau tias cov tshuaj muaj cov nyhuv hypoglycemic zoo.Vim tias GLP-1 ua lub luag haujlwm ntawm cov piam thaj hauv kev txhawb nqa kev tsim cov tshuaj insulin thiab tso tawm, cov kev tsis zoo tshwm sim xws li hypoglycemia thiab qhov hnyav nce los ntawm kev siv tshuaj tiv thaiv kab mob ntshav qab zib tsis tshwm sim.