Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity > 99.0% (HPLC) Hoobkas Zoo
Muab Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
Tom ntej: 2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Tshuaj npe | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a] pyrazine Hydrochloride |
Synonyms | Sitagliptin Triazole Hydrochloride;Sitagliptin Intermediate A |
CAS Nr | 762240-92-6 |
CAT Number | Qauv: RF-PI1193 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C6H7F3N4 · HCl |
Molecular Luj | 228.60 Nws |
Melting Point | 236.0 ~ 246.0 ℃ |
Solubility | Soluble hauv Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
Kev txheeb xyuas los ntawm HPLC | Lub sijhawm khaws cia ntawm cov qauv yog concordant nrog cov qauv siv |
Kev txheeb xyuas los ntawm IR | Ua raws |
Poob rau ziab | <0.50% |
Yam khoom muaj feem | |
Ib qho Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Hnyav Hlau | <20 ppm |
Purity / Analysis Method | > 99.0% (HPLC) |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) yog ib qho nruab nrab ntawm Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), uas yog qhov ncauj-bioavailable xaiv DPP4 inhibitor uas tau tshawb pom los ntawm kev ua kom zoo ntawm chav kawm ntawm β-aminoacid-derived DPP4 inhibitors.Nws txo qis DPP4 kev ua haujlwm nyob rau hauv ib qho kev txhawb nqa tom qab ib zaug kev tswj hwm txhua hnub, khaws cov qib ntawm cov kab mob tsis zoo GIP thiab GLP1 tom qab noj mov hauv ob qho tib si mob thiab mob ntev thiab txo cov ntshav qabzib yam tsis muaj qhov nce hauv hypoglycemia.Sitagliptin Phosphate (STG) yog siv los kho DM hom 2 vim nws txhim kho glycemic tswj los ntawm kev nce qib ntawm cov tshuaj hormones nquag incretin, GLP-1 (peptide-1) thiab GIP (glucose-dependent insulinotropic peptide).STG tau pom zoo los ntawm FDA hauv xyoo 2006.