Sofosbuvir CAS 1190307-88-0 Purity ≥99.0% (HPLC)
Lub npe | Sofosbuvir |
Synonyms | GS-7977;PSI-7977 |
CAS Nr | 1190307-88-0 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C22H29FN3O9P |
Molecular Luj | 529.45 ib |
Melting Point | 120.0 ~ 125.0 ℃ |
Qhov ntom | 1.41 ib |
Solubility | Soluble hauv DMF, DMSO, Ethanol |
Shipping Condition | Nyob rau hauv Ambient Kub |
COA & MSDS | Muaj |
Keeb kwm | Shanghai, Suav |
Txee lub neej | 36 Lub Hlis yog khaws cia kom raug |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
Kev txheeb xyuas | HPLC;RT |
Purity / Analysis Method | ≥99.0% (HPLC) |
EE | ≥99.0% |
Poob rau ziab | ≤ 1.0% |
Residue ntawm Ignition | ≤ 0.20% |
Ib leeg Impurity | ≤0.50% |
Tag nrho cov impurities | ≤ 1.0% |
Hnyav Hlau | ≤ 20ppm |
Residual Solvents | Ua tau raws li qhov yuav tsum tau ua ntawm specifications |
Methanol | ≤1500ppm |
TBME | ≤2500ppm |
Dichloromethane | ≤720ppm |
Tetrahydrofuran | ≤720ppm |
Toluene | ≤60ppm |
Test Standard | Enterprise Standard |
Kev siv | Sofosbuvir (CAS: 1190307-88-0) Kev kho tus kab mob siab C (HCV) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo
Sofosbuvir (CAS: 1190307-88-0) (cov ntawv sau npe raws li PSI-797, GS-7977) yog ib qho phosphoramidate prodrug thiab nucleotide polymerase inhibitor rau kev kho mob ntawm tus kab mob siab C (HCV).Nws raug nquahu kom siv ua ke nrog lwm cov tshuaj (xws li velpatasvir) rau kev kho thawj kab rau HCV genotypes 1, 2, 3, 4, 5, thiab 6. Nws yuav siv tau los ntawm kev ua raws li nucleotide analog inhibitor, ua muaj peev xwm tshwj xeeb inhibiting HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase.
Sau koj cov lus ntawm no thiab xa tuaj rau peb