Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API Hoobkas Zoo
Kev Lag Luam Kev Lag Luam Sorafenib Tosylate thiab Cov Neeg Nruab Nrab cuam tshuam:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS NO: 284462-37-9
4-Chloro-3-(Trifluoromethyl) phenyl Isocyanate CAS: 327-78-6
| Lub npe | Sorafenib |
| Synonyms | Sorafenib Free Base |
| CAS Nr | 284461-73-0 |
| CAT Number | RF-API 04 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C21H16ClF3N4O3 |
| Molecular Luj | 464.82 ib |
| Qhov ntom | 1.454 ± 0.06 g / cm3 |
| Solubility | Soluble hauv DMSO |
| Cov xwm txheej shipping | Ambient Kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau Off-White Powder |
| Purity / Analysis Method | ≥99.0% (HPLC) |
| Kev txheeb xyuas | H-NMR, MS |
| Poob rau ziab | ≤ 1.0% |
| Residue ntawm Ignition | ≤0.10% |
| Ib leeg Impurity | ≤0.20% (HPLC) |
| Tag nrho cov impurities | ≤1.0% (HPLC) |
| Hnyav Hlau | ≤ 20ppm |
| Clarity of Solution | Raws li Standard |
| Test Standard | Enterprise Standard |
| Kev siv | RCC & HCC |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Sorafenib Tosylate (CAS: 475207-59-1) yog ib yam tshiab ntawm ntau lub hom phiaj tshuaj tiv thaiv kab mob, tau tsim los ntawm German Bayer Pharmaceuticals, thiab nthuav tawm cov kev ua ub no nthuav dav hauv kev kuaj tsiaj ua ntej.Sorafenib muaj nyob rau hauv 200-mg ntsiav tshuaj rau kev tswj qhov ncauj thiab siv rau hauv kev kho mob ntawm RCC thiab HCC.Sorafenib Tosylate (CAS: 475207-59-1) tuaj yeem cuam tshuam rau cov qog hlwb thiab cov hlab ntsha.Nws muaj cov nyhuv antitumor ob npaug: nws tuaj yeem thaiv lub xov tooj ntawm tes teeb liab txoj hauv kev sib kho los ntawm RAF / MEK / ERK kom ncaj qha inhibit qog cell loj hlob, thaum tseem inhibiting VEGF thiab platelet derived growth factors (PDGF) receptors los tiv thaiv kev tsim cov qog ntshav tshiab. cov hlab ntsha, yog li indirectly inhibiting qog cell loj hlob.Sorafenib yog ib qho inhibitor ntawm Raf-1 thiab B-RAF nrog rau ntau yam tyrosine kinases.
