TCFH CAS 94790-35-9 Purity > 99.0% (HPLC) Hoobkas Coupling Reagents
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm TCFH (CAS: 94790-35-9) nrog cov khoom zoo.Ruifu Chemical muab cov txheej txheem tiv thaiv reagents thiab coupling reagents.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav TCFH,Please contact: alvin@ruifuchem.com
Tshuaj npe | N, N, N', N'-Tetramethylchloroformamidinium Hexafluorophosphate |
Synonyms | TCFH;Chloro-N, N, N', N'-Tetramethylformamidinium Hexafluorophosphate;N-[Chloro(dimethylamino)methylene]-N-Methyl-Methanaminium Hexafluorophosphate;Tetramethylchloroformamidinium Hexafluorophosphate |
Tshuag xwm txheej | Hauv Tshuag, Kev Tsim Khoom Loj |
CAS Nr | 94790-35-9 |
Molecular Formula | C5H12ClF6N2P |
Molecular Luj | 280.58 g / mol |
Melting Point | 99.0 ~ 108.0 ℃ |
Qhov ntom | 1.58 ib |
rhiab heev | Moisture Sensitive, Thaum tshav kub kub Sensitive |
Cia Temp. | Qhov chaw txias & qhuav (2 ~ 8 ℃) |
COA & MSDS | Muaj |
Qeb | Coupling Reagents |
Hom | Ruifu Tshuaj |
Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov | Ua raws |
Melting Point | 99.0 ~ 108.0 ℃ | 102.4 ~ 103.6 ℃ |
Poob rau ziab | <0.50% | 0.15% |
Purity / Analysis Method | > 99.0% (HPLC) | 99.9% |
Infrared Spectrum | Raws li tus qauv | Ua raws |
Proton NMR Spectrum | Raws li tus qauv | Ua raws |
Xaus | Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (2 ~ 8 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R40 - Cov pov thawj txwv ntawm cov nyhuv carcinogenic
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S22 - Tsis txhob nqus plua plav.
WGK Germany 3
FLUKA BRAND F CODE 3-10-21
N, N, N', N'-Tetramethylchloroformamidinium Hexafluorophosphate (TCFH) (CAS: 94790-35-9), coupling reagent rau peptide synthesis thiab pib cov khoom siv rau kev npaj lwm yam coupling reagents.TCFH yog ib qho zoo uas tsis yog-hygroscopic peptide synthesis coupling reagent.Raws li kev ua kom nquag plias ntawm cov khoom theem chemistry, TCFH feem ntau txhawb kev tsim cov carboxylic acid amine derivatives es tsis yog amide hauv cov txheej txheem sib txuas ntawm cov amino acids.Nws yog qhov tseem ceeb heev rau kev sib txuas ntawm cov amino acids hindered heev, thiab muaj cov yam ntxwv ntawm cov txheej txheem synthesis yooj yim thiab yooj yim thiab lub neej ntev.
TCFH yog ib qho kev nyab xeeb, pheej yig reagent rau ester thiab nyuaj amide synthesis.
TCFH raws li ib tug reagent muaj ntau yam zoo ib yam li kev lag luam:
- Vim yog lub zog sib txuas siab, nws yuav siv tau rau hauv cov tshuaj tiv thaiv yav dhau los tsuas yog ua tiav siv carbodiimide-mediated couplings, txuas ntxiv rau qhov no nws daim ntawv thov rau kev tsim cov esters, diacyl amides thiab acylation ntawm non-reactive amines.
- Nws yog cov khoom ruaj khov, ruaj khov, thaum khaws cia ib puag ncig 0 ° C
- Siv cov khoom sib txuas uas muaj dav dav, tus kws kho mob tuaj yeem nrhiav pom qhov zoo tshaj plaws reagent piv rau qhov sib npaug ntawm cov khoom tawm los thiab cov kev cuam tshuam sab nrog rau epimerization.
Tshaj li 2 feeb, mus rau 1,1,3,3-Tetramethylurea (2.5 mL, 21 mmol) / 10 mL toluene tov ib feem me me ntawm oxalyl chloride (2.0 mL, 23 mmol) tau ntxiv thaum cov tshuaj tiv thaiv sib xyaw. ntawm dej khov-dej da dej kub.Tom qab nplawm nyob rau hauv chav tsev kub rau 18 teev, cov tshuaj tiv thaiv sib tov yog concentrated nyob rau hauv txo lub siab mus rau ib tug ntim ntawm txog 5 mL thiab lub resulting precipitate tau sau los ntawm pom.Cov khoom sib sau tau yaj hauv li 20 mL dej thiab tom qab ntawd kho nrog potassium hexafluorophosphate (3.8g, 21 mmol) / 50 mL ntawm cov dej aqueous thaum cov sib tov tau sib xyaw ua ke ntawm chav tsev kub, kom tau txais cov dej nag dawb.Lub precipitate tau sau los ntawm kev pom thiab qhuav hauv lub tshuab nqus tsev.Tom qab ntawd cov khoom raug kho nrog kwv yees li 8 mL ntawm acetone thiab lim kom tshem tawm cov khoom insoluble.Lub resulting filtrate tau ntxiv nyob rau hauv me me rau 60 mL ntawm diethyl ether nrog rau lub zog stirring nyob rau hauv chav tsev kub.Cov khoom xav tau raug sau los ntawm kev pom thiab ziab hauv lub tshuab nqus tsev kom muab 4.5g (76%).