Telmisartan CAS 144701-48-4 Purity > 99.5% (HPLC) API Hoobkas

Lus piav qhia luv luv:

Lub npe tshuaj: Telmisartan

CAS: 144701-48-4 Nr

Purity:> 99.5% (HPLC)

Cov tsos mob: Dawb los yog Off-White Crystalline

Angiotensin II Receptor Antagonist

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

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Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Telmisartan Intermediates Nrog Siab Purity
Telmisartan CAS 144701-48-4
Tom ntej: Methyl 2-(p-Tolyl) Benzoate CAS 114772-34-8
2- (p-Tolyl) benzoic acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Tom ntej: Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Tom ntej: Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9

Chemical Properties:

Tshuaj npe	Telmisartan
Synonyms	4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl [2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Carboxylic Acid
CAS Nr	144701-48-4
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C33H30N4O2
Molecular Luj	514.63 ib
Melting Point	261.0 ~ 263.0 ℃
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb los yog Off-White Crystalline Hmoov
tsw	Yam ntxwv
Solubility	Sparingly Soluble nyob rau hauv Methylene Chloride, me ntsis Souble nyob rau hauv Methanol, Parctically Insoluble nyob rau hauv dej, Disolves nyob rau hauv 1M tshuaj Hydroxide
IR Identification	Yuav tsum ua raws li RS Infrared Absorption
HPLC Identification	Lub Sijhawm Retention of Major Peak yuav tsum sib haum rau RS
Purity / Analysis Method	> 99.5% (HPLC)
Poob rau ziab	<1.00%
Residue ntawm Ignition	<0.10%
Yam khoom muaj feem
Telmisartan Related Compound A	<0.10%
Telmisartan Amide	<0.10%
Telmisartan Related Compound B	<0.10%
Telmisartan Diacide	<0.10%
Telmisartan Tert-Butyl Ester	<0.20%
Telmisartan Unknown impurity	<0.20%
Unspecified impurity	<0.10%
Tag nrho cov impurities	<1.00%
Residual Solvents
Methanol	<0.30%
Ethanol	<0.50%
Methylene Dichloride	<0.06%
n-Hexane	<0.029%
Acetic Acid Ethyl Ester	<0.50%
Toluene	<0.089%
Acetic acid	<0.50%
Hnyav Hlau	<10ppm
Arsenic (As)	<1.00ppm
Lead (Pb)	<1.00ppm
Cadmium (Cd)	<1.00ppm
Particle Loj	D90 Tsis ntau tshaj 15μm
Qhov ceev (g / cc)	0.11-0.20 Nws
Tapping Density (g / cc)	0.22-0.30 Nws
Residual Tshuaj tua kab	Tsis zoo
Tag Nrho Phaj suav	<1000cfu/g
Poov & Pwm	<100cfu/g
E. Coli	Tsis zoo
Salmonella	Tsis zoo
Test Standard	Enterprise Standard;USP 41 Txuj
Kev siv	API

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

Telmisartan (CAS: 144701-48-4) yog benzimidazole derivative thiab non-peptide angiotensin II receptor antagonist nrog antihypertensive khoom.Telmisartan xaiv antagonizes angiotensin II khi rau AT1 subtype receptor, nyob rau hauv vascular du leeg thiab qog adrenal.Qhov kev tawm tsam ua rau vasodilation thiab inhibits angiotensin II-mediated aldosterone ntau lawm, uas ua rau txo qis hauv sodium thiab dej nrog rau kev nce ntxiv ntawm cov poov tshuaj tso tawm ua rau txo qis hauv ntshav siab.Telmisartan yog ib yam tshiab ntawm cov tshuaj ntshav siab, yog siv ib leeg los yog ua ke nrog lwm cov chav kawm ntawm antihypertensives rau kev kho mob ntshav siab.Telmisartan yog tsim los ntawm German kws tshuaj lub tuam txhab Boehringer Ingelheim;nws tau txais German patent EP502,314 hauv 1991, thawj zaug pom zoo nkag mus rau Asmeskas kev lag luam thaum lub Kaum Ib Hlis 1998, thiab tom qab ntawd nkag mus hauv German, Philippines, Australian, Belgium, British, thiab lwm yam lag luam.