Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0% ~ 101.0% API Hoobkas High Purity
Muab Temozolomide thiab Lwm Yam Khoom Siv:
Tom ntej: Temozolomide CAS 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Tshuaj npe | Temozolomide |
| Synonyms | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]Tetrazine-8-Carboxamide |
| CAS Nr | 85622-93-1 |
| CAT Number | RF-API 29 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C6H6N6O2 |
| Molecular Luj | 194.15 Nws |
| Melting Point | 212 ℃ dec. |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau lub teeb Pink hmoov |
| Kev txheeb xyuas | Los ntawm IR, HPLC |
| Residual Solvents | Dimethyl sulfoxide ≤0.50% |
| Yam khoom muaj feem | |
| Impurity AIC | ≤0.10% |
| Ib leeg Impurity | ≤0.10% |
| So Unknown Impurities | ≤ 0.30% |
| Tag nrho cov impurities | ≤ 0.30% |
| Hnyav Hlau | ≤10ppm |
| Poob rau ziab | ≤0.50% |
| Residue ntawm Ignition | ≤0.10% |
| Assay | 99.0% ~ 101.0% (HPLC ntawm lub hauv paus qhuav) |
| Test Standard | Enterprise Standard |
| Kev siv | Active Pharmaceutical Ingredients (API) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Temozolomide (CAS: 85622-93-1) nrog cov khoom zoo.Temozolomide (TMZ) yog tus neeg sawv cev ntawm qhov ncauj alkylating siv los kho Glioblastoma Multiforme (GBM) thiab Astrocytomas, Metastatic Melanoma.
Temozolomide yog thawj qhov ua tau zoo ntawm qhov ncauj imidazole thiab tetrazine-chav kawm tshuaj tiv thaiv kab mob uas yog nyob rau tiam thib ob ntawm tus neeg sawv cev alkylating nrog cov tshuaj tiv thaiv kab mob tsis muaj lub siab ua haujlwm tom qab kev tswj hwm qhov ncauj.Nws yog tus cwj pwm los ntawm kev nkag mus tau yooj yim los ntawm cov ntshav-hlwb teeb meem, kev ua siab ntev thiab tsis raug cuam tshuam nrog lwm cov tshuaj toxicity, thiab muaj kev sib koom ua ke nrog kev siv xov tooj cua uas tsim nyog rau kev kho mob malignant glioma rov tshwm sim tom qab kev kho mob xws li glioblastoma multiforme qog lossis degenerative astrocytoma.Nws yog thawj kab tshuaj rau kev kho mob ntawm metastatic melanoma.
Temozolomide tau ua thawj zaug los ntawm Cancer Research UK Group, thiab tom qab ntawd raug xa mus rau Schering-Plough Company (Tebchaws Meskas) rau kev txhim kho.Nws muaj cov qauv tshuaj tshiab thiab belongs rau plaub-imidazole derivative.Nyob rau hauv 1999, nws tau raug pom zoo rau nkag mus rau hauv kev ua lag luam nyob rau hauv EU thiab lub US nyob rau hauv qhov kev tso cai qhia nyob rau hauv lub tebchaws United States yog tsuas yog rau thib ob-kab kev kho mob ntawm glioblastoma multiforme thiab degenerative hnub qub gliomas thiab pom zoo indications ntawm EU yog rau kev kho mob tsim los yog relapsing glioblastoma multiforme. uas twb tau mus rau cov pa kev kho mob.Kev ua tau zoo ntawm temozolomide ntawm kev kho glioblastoma multiforme tau txais kev lees paub ntau dua hauv Tebchaws Europe.
