Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Hoobkas Anti-HIV High Quality

Lus piav qhia luv luv:

Lub npe: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7 Nr

Dawb rau Yuav luag Dawb Crystals lossis Crystalline Hmoov

Kev Ntsuas: 98.0% ~ 102.0%

Ib tug prodrug rau Tenofovir, siv nyob rau hauv kev kho mob ua ke rau kev kho mob ntawm tus kab mob HIV-1

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Kev muag khoom lag luam Tenofovir Related Intermediates:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Tom ntej: Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Chemical Properties:

Tshuaj npe	Tenofovir Alafenamide Hemifumarate
Synonyms	TAF;GS-7340 Hemifumarate
CAS Nr	1392275-56-7
CAT Number	RF-API 91
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms
Molecular Formula	C25H33N6O9P
Molecular Luj	592.55 ib
Cia Kub	Muab ntim rau hauv Qhuav, Chav Kub Kub
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Yuav luag Dawb Crystals lossis Crystalline Hmoov
Solubility	Soluble hauv Dimethylformamide, thiab Methanol;Sparingly Soluble hauv dej thiab THF;Me ntsis Soluble hauv Acetonitrile thiab Insoluble hauv Dichloromethane thiab Toluene
Kev Taw Qhia A	IR absorption spectra yuav tsum ua raws li kev siv
Kev Qhia B	Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem hauv cov ntsiab lus kev txiav txim siab chromatogram ua raws li cov lus qhia siv.
Kev txheeb xyuas C	Fumaric Acid tuav lub sij hawm ntawm lub ncov loj hauv cov ntsiab lus txiav txim siab chromatogram ua raws li lub ncov ntawm kev siv
Cov ntsiab lus dej (los ntawm KF)	≤ 1.0%
Clarity of Solution	Yeej tsis pom cov khoom hauv 2% (w/v) ntawm Methanol Solution kom meej
Residual Solvent
Cov tshuaj acetonitrile	≤410ppm
Ethanol	≤5000ppm
Dichloromethane	≤600ppm
Toluene	≤890ppm
Residue ntawm Ignition	≤0.10%
Hnyav Hlau	≤ 20ppm
Yam khoom muaj feem
PMPA	≤ 1.0%
Tom ntej: PMPA Anhydride	≤ 0.75%
Ib leeg Phenyl PMPA	≤ 1.0%
Tej yam tsis meej tsis meej	≤ 0.15%
Tag nrho cov impurities	≤ 2.0%
Isomer	≤ 1.0%
Cov ntsiab lus ntawm Fumaric Acid	9.0% ~ 13.0% (raws li anhydrous hauv paus)
Microbial txwv
Tag nrho Aerobic Microbial suav	≤1000CFU / g
Tag nrho cov poov xab thiab pwm suav	≤100CFU / g
Escherichia Coli	Tsis muaj
Assay	98.0% ~ 102.0% (raws li anhydrous thiab hnyav-dawb hauv paus)
Test Standard	Enterprise Standard

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, yog nucleotide reverse transcriptase inhibitor (NRTIs) thiab cov tshuaj tshiab ntawm Tenofovir (TFV).Los ntawm thaiv kev thim rov qab transcriptase, TAF tiv thaiv HIV los ntawm kev sib npaug thiab tuaj yeem txo tus nqi ntawm HIV hauv lub cev.Tenofovir alafenamide yog ib qho tshuaj tiv thaiv, uas txhais tau hais tias nws yog ib qho tshuaj tsis muaj zog.Hauv lub cev, tenofovir alafenamide hloov mus rau Tenofovir diphosphate (TFV-DP).Tenofovir Alafenamide Fumarate tau pom zoo nyob rau lub Kaum Ib Hlis 2015 rau kev kho mob HIV-1.