Tenofovir CAS 147127-20-6 Assay 98.0% ~ 102.0% API Anti-HIV Hoobkas
Kev muag khoom lag luam Tenofovir Related Intermediates:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Tom ntej: Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Lub npe | Tenofovir |
Synonyms | (R)-PMPA;(R)-9-(2-Phosphonomethoxypropyl)Adenine |
CAS Nr | 147127-20-6 |
CAT Number | RF-API 07 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C9H14N5O4p |
Molecular Luj | 287.22 ib |
Melting Point | 276.0-280.0 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Yuav luag Dawb Crystalline Hmoov |
Assay / Analysis Method | 98.0% ~ 102.0% (raws li anhydrous hauv paus) |
Solubility | Me ntsis soluble hauv dej (0.1g hauv 100ml);Xyaum Insoluble hauv Methanol (0.01g hauv 100ml thiab tshaj) |
Identification UV | Absorbance ntawm txog 261nm |
Kev txheeb xyuas HPLC | Lub sijhawm khaws cia ntawm tus thawj coj ncov hauv cov qauv xeem yuav tsum sib phim nrog tus qauv |
Sulphate Ash | ≤ 1.5% |
Dej (KF) | ≤ 3.0% |
Specific Optical Rotation | -19.0 ° ~ -23.0 ° (ntawm 25 ℃ anhydrous hauv paus) |
PMPA Monoester impurity | ≤1.5% (HPLC) |
Ib leeg Max Impurity | ≤0.5% (HPLC) |
Tag nrho cov impurities | ≤ 3.0% (HPLC) |
Enantiomeric Purity yog qhov zoo | ≤0.5% (HPLC) |
9-Propenyl Adenine | ≤75ppm (HPLC) |
Test Standard | Enterprise Standard |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo.
Tenofovir (CAS: 147127-20-6) yog ib qho acyclic phosphonate nucleotide analogue thiab thim rov qab-transcriptase inhibitor (NtRTI).Nws yog siv los ua tus neeg sawv cev tiv thaiv kab mob HIV.Antiviral.Tenofovir disoproxil (Viread) yog thawj nucleotide analogue pom zoo los ntawm American FDA los kho tus kab mob HIV-1.Tenofovir yog ib hom tshuaj siv los kho tus kab mob siab B mob ntev nrog rau kev tiv thaiv thiab kho kab mob HIV / AIDS.Nws inhibits qhov kev ua ntawm HIV thim rov qab transcriptase los ntawm kev sib tw nrog lub ntuj substrate deoxyadenosine 5'-triphosphate, ua rau txiav tawm ntawm DNA saw.