Thiamphenicol CAS 15318-45-3 Purity > 99.5% (HPLC) Hoobkas
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Tshuaj npe | Thiamphenicol |
Synonyms | D-Thiophenicol;2,2-Dichloro-N-[(1R,2R)-1,3-Dihydroxy-1-[4-(Methylsulfonyl)phenyl]-2-propyl]acetamide;D-Threo-2,2-Dichloro-N-(β-Hydroxy-α-[Hydroxymethyl]-4-[Methylsulfonyl]phenethyl)acetamide |
CAS Nr | 15318-45-3 |
CAT Number | Qauv TSIS MUAJ: RF-PI2043 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C12H15Cl2NO5S |
Molecular Luj | 356.22 ib |
Solubility | Soluble hauv Acetonitrile lossis DMF.Me ntsis Soluble hauv dej |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb Crystalline hmoov |
Melting Point | 163.0 ~ 167.0 ℃ |
Kev sib hloov tshwj xeeb [α]20/D | -21.0° ~ 24.0° C = 5 hauv DMF |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.20% |
Yam khoom muaj feem | |
Ib qho Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Chlorides (Cl) | ≤ 0.02% |
Hnyav Hlau | ≤10ppm |
Purity / Analysis Method | > 99.0% (HPLC) |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Broad Spectrum Antimicrobials;Veterinary Medicine Tshuaj |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Thiamphenicol (CAS: 15318-45-3) yog broad-spectrum tshuaj tua kab mob chloramphenicol.Nws muaj cov qauv tshuaj zoo sib xws nrog chloramphenicol.Nws cov methyl sulfone hloov cov nitro ntawm chloramphenicol, uas txo nws cov toxicity, thiab nyob rau hauv vivo nws antibacterial kev ua si yog 2.5-5 npaug zog dua chloramphenicol.Rau cov kab mob gram-zoo, xws li streptococcus pneumoniae thiab hemolytic streptococcus, nws muaj cov kab mob muaj zog heev, thaum cov kab mob gram-tsis zoo, xws li Neisseria gonorrhoeae, meningococcus, ntsws Bacteroides, E. coli, Vibrio cholerae, Shigella thiab inacill. nws kuj muaj zog antibacterial nyhuv.Rau cov kab mob anaerobic, Rickettsia thiab amoeba, nws muaj cov kab mob tua kab mob hauv qee qhov.Nws muaj tib yam tshuaj tiv thaiv kab mob nrog chloramphenicol, uas feem ntau inhibits cov synthesis ntawm cov kab mob protein.Cov tshuaj no yog nqus sai sai los ntawm kev tswj qhov ncauj, uas ncav cuag cov ntshav siab tshaj plaws hauv ob teev.Nws ib nrab-lub neej yog 5 teev, uas yog ntev tshaj li chloramphenicol.Cov kab mob no muaj cov kab mob ua tiav rau nws thiab chloramphenicol, thaum cov kab mob muaj qee qhov cuam tshuam rau nws thiab tetracycline.Thiamphenicol yog ib qho tshuaj tua kab mob uas tsim los kho cov kab mob sib kis hauv nyuj, npua thiab nqaij qaib.Nws yog siv los ua cov dej soluble thiamphenicol glycine hydrochloride rau kev kho parenteral thiab ua ib qho kev sib xyaw ua ke ntawm thiamphenicol puag thiab pob kws hmoov txhuv nplej siab, (4: 1) los yog lwm yam tov khoom, rau kev siv qhov ncauj.Thiamphenicol yog tshuaj tua kab mob.Nws yog methyl-sulfonyl analogue ntawm chloramphenicol thiab muaj qhov zoo sib xws ntawm kev ua haujlwm, tab sis yog 2.5 mus rau 5 zaug li muaj zog.Zoo li chloramphenicol, nws yog insoluble nyob rau hauv dej, tab sis heev soluble nyob rau hauv lipids.Nws yog siv nyob rau hauv ntau lub teb chaws raws li ib tug veterinary tshuaj tua kab mob, tab sis muaj nyob rau hauv Tuam Tshoj, Morocco thiab Ltalis siv rau tib neeg.Feem ntau yog rau qaib, ducks, geese dab sluggish, enteritis, rub cov quav daj-dawb, airsacculitis, peritonitis, perihepatitis, salpingitis, vitelline peritonitis, follicle deformation, plab hnyuv mucosa congestive thiab los ntshav, mesentery ua pa nyuaj thiab ua pa nyuaj. tshwm sim los ntawm refractory E.coli, pasteurella anatipestifer, salmone, thiab lwm yam.Rau cov tsiaj nyeg thiab nqaij qaib mob hnyav lossis mob ua pa ntev, hnoos, hnoos, qhov ntswg.Kuj tseem muaj cov txiaj ntsig zoo ntawm E.coliillness, salmonella, eperythrozoonosis, kab mob staphylococci, fowl cholera, necrotizing enterocolitis thiab lwm yam kab mob.