Trityl Olmesartan Acid CAS 761404-85-7 Purity > 98.5% (HPLC) Olmesartan Medoxomil Hoobkas
Ruifu Chemical Supply Olmesartan Medoxomil Intermediates Nrog Cov Khoom Zoo:
Tom ntej: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
Tom ntej: 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Tom ntej: Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Tom ntej: Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Tom ntej: Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Tom ntej: Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Tshuaj npe | Trityl Olmesartan Acid |
Synonyms | TOA;Olmesartan N1-Trityl impurity;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl methyl]-1H-Imidazole-5-Carboxylic Acid |
CAS Nr | 761404-85-7 |
CAT Number | Qauv: RF-PI1875 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C43H40N6O3 |
Molecular Luj | 688.82 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Kev txheeb xyuas los ntawm HPLC | Lub sijhawm khaws cia ntawm lub ncov loj hauv chromatogram ntawm tus qauv sib raug rau tus qauv raws li tau txais hauv purity thiab lwm yam tshuaj |
Purity / Analysis Method | > 98.5% (HPLC) |
Dej (KF) | <0.50% |
Residue ntawm Ignition | <0.20% |
Olmesartan | <1.00% |
impurity A | <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]- 4-yl]methyl}-1H-Imidazole-5-carboxylic acid |
Impurity B | <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]- 4-yl]methyl}-1H-Imidazole-5-carboxylic acid |
Cov impurity C | <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl}-1H -Imidazole-5-carboxylic acid |
Lwm Yam Ntau Tshaj Ib Leeg Impurity | <1.00% |
Tag nrho cov impurities | <1.50% |
Heavy Metals (raws li Pb) | <20 ppm |
Test Standard | Enterprise Standard |
Kev siv | Olmesartan Medoxomil (CAS: 144689-63-4) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Trityl Olmesartan Acid (CAS: 761404-85-7) yog ib qho nruab nrab lossis impurity ntawm Olmesartan Medoxomil (CAS: 144689-63-4), tshuaj tiv thaiv hypertensive.Olmesartan Medoxomil (Benicar) yog ib qho kev sib xyaw uas yog hydrolyzed rau Olmesartan uas yog xaiv AT1 subtype angiotensin II receptor antagonist.Olmesartan Medoxomil tau hloov mus rau Olmesartan thaum nqus los ntawm txoj hnyuv.Olmesartan yog qhia rau kev kho mob ntshav siab.Nws tuaj yeem siv ib leeg lossis ua ke nrog lwm cov tshuaj tiv thaiv kab mob.Olmesartan Medoxomil exerts nws pharmacological zog los ntawm kev thaiv kev khi ntawm angiotensin II rau AT1 receptors nyob rau hauv vascular leeg;Nws yog li ntawd ywj siab ntawm angiotensin II synthesis pathways, tsis zoo li ACE inhibitors.