Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Purity > 98.5% (HPLC) Hoobkas
Ruifu Chemical Supply Olmesartan Medoxomil Intermediates Nrog Cov Khoom Zoo:
Tom ntej: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
Tom ntej: 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Tom ntej: Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Tom ntej: Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Tom ntej: Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Tom ntej: Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Tshuaj npe | Trityl Olmesartan Ethyl Ester |
Synonyms | Olmesartan Ethyl Ester Trityl impurity;Olmesartan Medoxomil Impurity 30;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl methyl]-1H-Imidazole-5-Carboxylic Acid Ethyl Ester;Ethyl 4-(2-hydroxypropan-2-yl)-2-Propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl methyl)-1H-Imidazole-5-Carboxylate |
CAS Nr | 144690-33-5 |
CAT Number | Qauv: RF-PI1873 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C45H44N6O3 |
Molecular Luj | 716.87 ib |
Melting Point | 161 ℃ |
Qhov ntom | 1.18 ± 0.1g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Purity / Analysis Method | > 98.5% (HPLC) |
Cov ntsiab lus dej (KF) | <0.50% |
Residue ntawm Ignition | <0.20% |
Impurity Ⅰ | <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl ]methyl}-1H-imidazole-5-carboxylic ethyl ester |
Cov impurity Ⅱ | <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]- 4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester |
Cov impurity yog ib qho yooj yim rau nruab | <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H -imidazole-5-carboxylic ethyl ester |
Lwm Yam Ntau Tshaj Ib Leeg Impurity | <1.00% |
Tag nrho cov impurities | <1.50% |
Test Standard | Enterprise Standard |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Trityl Olmesartan Ethyl Ester (CAS: 144690-33-5) yog ib qho impurity ntawm Olmesartan Medoxomil (CAS: 144689-63-4).Olmesartan Medoxomil yog ib qho angiotensin II receptor antagonist siv los kho cov ntshav siab, Siv ua tshuaj tiv thaiv ntshav siab.Olmesartan ua haujlwm los ntawm kev thaiv kev khi ntawm angiotensin II rau AT1 receptors hauv cov leeg nqaij.Los ntawm kev thaiv cov kev sib txuas es tsis yog kev sib txuas ntawm angiotensin II, Olmesartan inhibits cov lus qhia tsis zoo ntawm renin secretion.Olmesartan Medoxomil tau tsim tawm hauv Teb Chaws Asmeskas raws li Benicar@, kev kho qhov ncauj qhov ncauj rau ntshav siab.Olmesartan Medoxomil yog sai thiab ua tiav bioactivated los ntawm ester hydrolysis rau nws cov nquag metabolite, olmesartan, thaum nqus los ntawm txoj hnyuv.