TTBB CAS 124750-51-2 Purity > 96.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
CAS Nr .: 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Tshuaj npe | 5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole |
Synonyms | TTBB;BBTT;5-[4'-Bromomethyl-(1,1'-Biphenyl)-2-yl]-1-Triphenylmethyltetrazole;N-(Triphenylmethyl)-5-(4'-Bromomethylbiphenyl-2-yl-) tetrazole;Olmesartan Impurity 12;Losartan Bromo N1-Trityl impurity |
CAS Nr | 124750-51-2 |
CAT Number | Qauv: RF-PI1878 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 150MT / Xyoo |
Molecular Formula | C33H25BrN4 |
Molecular Luj | 557.48 ib |
Melting Point | 152.0 ~ 155.0 ℃ |
Qhov ntom | 1.28 ± 0.10g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Yuav luag Dawb Hmoov |
Purity / Analysis Method | > 96.0% (HPLC) |
Poob rau ziab | <0.50% |
impurity A | <2.00% (HPLC) 5-(4-Methyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole |
Impurity B | <2.00% 5-(4'.4'-Dibromomethyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole |
Infrared Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Irbesartan (CAS: 138402-11-6);Olmesartan Medoxomil impurity |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole (TTBB) (CAS: 124750-51-2) yog ib qho nruab nrab ntawm Irbesartan (CAS: 138402-11) -6).Irbesartan yog siv rau kev kho mob ntshav siab, nrog rau cov ntshav qab zib nephropathy nrog cov ntshav siab creatinine thiab proteinuria (> 300 mg / hnub) hauv cov neeg mob ntshav qab zib hom 2 thiab ntshav siab.Irbesartan kuj tseem siv los ua tus neeg sawv cev thib ob hauv kev kho mob congestion.Irbesartan yog angiotensin II receptor antagonist siv tsuas yog siv rau kev kho mob ntshav siab.Nws tau tsim los ntawm Sanofi Research (tam sim no ib feem ntawm Sanofi-Aventis).Nws tau koom ua lag luam los ntawm Sanofi-Aventis thiab Bristol-Myers Squibb nyob rau hauv lub npe lag luam Aprovel, Karvea, thiab Avapro.