Valsartan CAS 137862-53-4 Assay 98.0 ~ 102.0% API
Chaw tsim tshuaj paus Supply Valsartan thiab Related Intermediates:
Valsartan CAS Nr .: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-Ome · HCl) CAS: 6306-52-1
Tshuaj npe | Valsartan |
Synonyms | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
CAS Nr | 137862-53-4 |
CAT Number | RF-API 32 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C24H29N5O3 |
Molecular Luj | 435.52 ib |
Melting Point | 116.0 ~ 117.0 ℃ |
Kev ruaj ntseg | Hygroscopic |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White hmoov;Tsis muaj ntxhiab tsw, hygroscopic |
Kev txheeb xyuas | IR spectrum ntawm tus qauv sib tw nrog cov qauv siv spectrum |
Kev txheeb xyuas | Lub sijhawm khaws cia ntawm lub ncov loj nyob rau hauv chromatogram ntawm kev tshuaj ntsuam kev npaj sib raug rau cov txheej txheem kev npaj, raws li tau txais hauv Assay. |
Solubility | Soluble hauv Methanol thiab Ethanol, Sparingly Soluble hauv Ethylacetate, Me ntsis Soluble hauv Dichloromethane, Insoluble hauv dej |
Moisture (KF) | ≤ 1.00% |
Absorbance (420 hli) | ≤0.02% (λ=420nm, C = 0.05g/ml, L = 1cm) |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Yam khoom (HPLC) | |
Butyryl-Valsartan | ≤ 0.20% |
Benzyl-Valsartan yog ib qho khoom noj khoom haus | ≤0.10% |
Tib Unknown Inpurity | ≤0.10% |
Tag nrho cov impurities | ≤0.30% (tsis suav D-Valsartan) |
Residual Solvents (GC) | |
Methanol | ≤3000ppm |
Ethyl Acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Purity / Analysis Method | > 99.0% (HPLC xam los ntawm cov dej tsis muaj dej, tsis muaj kuab lom) |
Test Standard | Tebchaws Asmeskas Pharmocopoeia (USP) |
Kev siv | Active Pharmaceutical Ingredients (API) |
Valsartan (CAS: 137862-53-4) Cov txheej txheem ntau lawm
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab chaw muag khoom ntawm Valsartan (CAS: 137862-53-4) nrog cov khoom zoo.Valsartan yog nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, muaj peev xwm rau ntshav siab thiab kev tshawb fawb plawv.
Valsartan's antihypertensive cov teebmeem muaj zog dua li cov enalapril thiab yog qhov tsim nyog rau kev kho mob ntshav siab, mob me mus rau theem pib ntshav siab, thiab tshwj xeeb tshaj yog mob ntshav siab los ntawm lub raum puas.Nws tuaj yeem txo cov proteinuria rau cov neeg mob ntshav siab uas muaj ntshav qab zib lossis lub siab ua haujlwm, thiab nws tuaj yeem txhawb nqa uric acid thiab urinary sodium los tiv thaiv lub raum.Valsartan kuj tseem tsim nyog rau kev txo qis kev mob plawv rau cov neeg mob uas muaj kev pheej hmoo siab (sab laug ventricular tsis ua haujlwm lossis ua haujlwm tsis zoo) tom qab muaj lub plawv nres.