Vidarabine (Ara-A) CAS 5536-17-4 Purity≥99.0% (HPLC) Lub Hoobkas Zoo
Chaw tsim tshuaj paus Supply Arabinonucleosides Intermediates nrog siab purity
Vidarabine;Ara-A;CAS: 5536-17-4 Nr
Arabinofuranosyluracil;Ara-U;CAS: 3083-77-0 Nr
Cytarabine;Ara-C;CAS: 147-94-4 Nr
Tshuaj npe | Vidarabine |
Synonyms | Ara-A;Arabinoadenosine;Adenine 9-β-D-Arabinofuranoside;Vira-A |
CAS Nr | 5536-17-4 ib |
CAT Number | Qauv: RF-PI220 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C10H13N5O4 |
Molecular Luj | 267.25 Nws |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Solubility | Xim tsis meej |
Purity / Analysis Method | ≥99.0% (HPLC) |
UV Cov ntsiab lus | ≥98% (nyob rau hauv qhuav) |
Kev sib hloov tshwj xeeb [a]D20 | -56.0° ~ 65.0° (C = 1 in DMF) |
Adenine | ≤0.50% |
Adenosine | ≤0.50% |
Ara- Ua | ≤0.50% |
Melting Point | 260.0 ~ 265.0 ℃ |
Hnyav Hlau | ≤ 20ppm |
Test Standard | Enterprise Standard |
Cia Kub | Khaws ntawm 0 ~ 8 ℃ |
Kev siv | API;Pharmaceutical Intermediates |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
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Vidarabine (CAS: 5536-17-4), yog ib qho tshuaj tiv thaiv kab mob uas tawm tsam herpes simplex thiab varicella zoster viruses.Vidarabine (CAS: 5536-17-4) yog ib qho neurotransmitter uas ua raws li qhov nyiam endogenous agonist ntawm txhua hom adenosine receptor subtypes.Vidarabine (CAS: 5536-17-4) yog ib qho inhibitor ntawm A cyclase thiab DNA Polymerase.Adenine 9-beta-D-arabinofuranoside (ara-A) yog ib qho hluavtaws tsim purine nucleoside uas siv hauv kev tshawb fawb ntawm tes.Nws tau nquag siv hauv kev tshawb fawb los tiv thaiv kab mob nrog hepadnaviridae thiab kab mob herpes simplex.Lub nucleoside ara-A cuam tshuam nrog cov kab mob DNA synthesis, tab sis tsuas yog nyob rau hauv nws cov active phosphorylated daim ntawv.
Vidarabine (CAS: 5536-17-4) yog tshuaj tua kab mob nucleoside cais tawm ntawm Streptomyces antibioticus.Nws muaj qee yam tshuaj antineoplastic thiab muaj kev ua haujlwm dav dav tiv thaiv DNA kab mob hauv cov kab lis kev cai ntawm tes thiab kev ua haujlwm tseem ceeb tiv thaiv kab mob los ntawm ntau yam kab mob xws li kab mob herpes, VACCINIA VIRUS thiab varicella zoster virus.Vidarabine (CAS: 5536-17-4) muaj peev xwm ntawm inhibiting acyclovir-resistant / TK-deficient mutants ntawm HSV thiab VZV, vim hais tias nws yog phosphorylated rau nws active vidarabine-triphosphate daim ntawv los ntawm cellular kinases thiab tsis yog nyob ntawm seb nws ua kom muaj zog ntawm lub cev. viral TK.
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