Homotaurine Tramiprosate CAS 3687-18-1 Purity >99.5% (Titration) Factory High Quality
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Homotaurine (CAS: 3687-18-1) with high quality, commercial production. To buy Homotaurine, please contact: alvin@ruifuchem.com
Chemical Name | Homotaurine |
Synonyms | Tramiprosate; 3-Amino-1-Propanesulfonic Acid; 3-Aminopropane-1-Sulfonic Acid; 3-APS |
CAS Number | 3687-18-1 |
CAT Number | RF-PI1676 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C3H9NO3S |
Molecular Weight | 139.17 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Needle Crystal or Crystalline Powder |
Odor | Odorless and Subacid |
Solubility | Soluble in Water; Slightly Soluble in Ethanol |
Purity / Analysis Method | >99.5% (Titration) |
Melting Point | 285.0~295.0℃ |
Loss on Drying | <0.20% |
Residue on Ignition | <0.10% |
Clarity of Solution | Colorless and Clear (50 mg/ml, H2O) |
Heavy Metals (as Pb) | <0.001% |
Arsenic (as As) | <0.0002% |
Chloride (as Cl) | <0.01% |
Sulphate (as SO4) | <0.01% |
Ammonium Salt (as NH4) | <0.02% |
Readily Carbonizable Substance | Colorless Solution |
Infrared Spectrum | Infrared Spectrum |
NMR | Consistent With Structure |
Test Standard | Enterprise Standard |
Usage | API; Pharmaceutical Intermediates; GABA Antagonist |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
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Homotaurine (CAS: 3687-18-1), also known as Tramiprosate, is a gamma-Aminobutyric acid (GABA) receptor agonist and a glycosaminoglycan mimetic used in the treatment of Alzheimer's disease. Homotaurine is a sulfated glycosaminoglycan mimetic that was reported to bind soluble Aβ and inhibit the interaction of Aβ with endogenous glycosaminoglycans, thereby preventing β-sheet formation. Conversely, tramiprosate was also reported to promote tau polymerization into fibrillar aggregates. It is also an analog of GABA that can act as a partial agonist of GABAA receptors, as well as an antagonist at GABAB receptors.
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