Homotaurine Tramiprosate CAS 3687-18-1 Purity >99.5% (Titration) Factory High Quality

Short Description:

Chemical Name: Homotaurine 

Synonyms: Tramiprosate

CAS: 3687-18-1

Purity: >99.5% (Titration)

White Needle Crystal or Crystalline Powder

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Homotaurine (CAS: 3687-18-1) with high quality, commercial production. To buy Homotaurine, please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Homotaurine
Synonyms Tramiprosate; 3-Amino-1-Propanesulfonic Acid; 3-Aminopropane-1-Sulfonic Acid; 3-APS 
CAS Number 3687-18-1
CAT Number RF-PI1676
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C3H9NO3S
Molecular Weight 139.17
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Needle Crystal or Crystalline Powder
Odor Odorless and Subacid 
Solubility Soluble in Water;  Slightly Soluble in Ethanol
Purity / Analysis Method >99.5% (Titration) 
Melting Point 285.0~295.0℃
Loss on Drying <0.20%
Residue on Ignition <0.10%
Clarity of Solution Colorless and Clear (50 mg/ml, H2O)
Heavy Metals (as Pb) <0.001%
Arsenic (as As) <0.0002%
Chloride (as Cl) <0.01%
Sulphate (as SO4) <0.01%
Ammonium Salt (as NH4) <0.02%
Readily Carbonizable Substance Colorless Solution
Infrared Spectrum Infrared Spectrum
NMR Consistent With Structure
Test Standard Enterprise Standard
Usage API; Pharmaceutical Intermediates; GABA Antagonist

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

1

FAQ:

Application:

Homotaurine (CAS: 3687-18-1), also known as Tramiprosate, is a gamma-Aminobutyric acid (GABA) receptor agonist and a glycosaminoglycan mimetic used in the treatment of Alzheimer's disease. Homotaurine is a sulfated glycosaminoglycan mimetic that was reported to bind soluble Aβ and inhibit the interaction of Aβ with endogenous glycosaminoglycans, thereby preventing β-sheet formation. Conversely, tramiprosate was also reported to promote tau polymerization into fibrillar aggregates. It is also an analog of GABA that can act as a partial agonist of GABAA receptors, as well as an antagonist at GABAB receptors.

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