2,4,5-Trifluorophenylacetic Asid CAS 209995-38-0 Pite ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Entèmedyè
Pwovizyon pou sitagliptin fosfat monoidrat entèmedyè ki gen rapò:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-trifluorofenilasetik asid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Asid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Entèmedyè CAS 486460-21-3
Non Chimik | 2,4,5-Trifluorophenylacetic asid |
Nimewo CAS | 209995-38-0 |
Nimewo CAT | RF-PI1191 |
Estati Stock | Nan Stock, Pwodiksyon Echèl Jiska Tòn |
Fòmil molekilè | C8H5F3O2 |
Pwa molekilè | 190.12 |
Pwen k ap fonn | 121.0 a 125.0 ℃ |
Solibilite | Soluble nan metanol |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Poud blan pou blan |
Pite / Metòd analiz | ≥99.5% (GC) |
Imidite (KF) | ≤0.50% |
Rezid sou Igniton | ≤0.50% |
Enpurte total | ≤0.50% |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pake: Boutèy, sache papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an.
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite.
2,4,5-Trifluorophenylacetic Asid (CAS: 209995-38-0) se yon entèmedyè nan Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) yo itilize pou trete DM tip 2 paske li amelyore kontwòl glisemi lè li ogmante nivo òmòn enkretin aktif, GLP-1 (peptide-1) ak GIP (peptide insulinotrop ki depann de glikoz).Aktivasyon enkretin sa yo nan selil β-pankreyas yo lakòz ogmante nivo siklik adenosine monofosfat (cAMP) ak kalsyòm intraselilè, ak sekresyon ensilin ki vin apre a ki depann de glikoz (2).Medikaman ipoglisemi sa a fè pati yon nouvo klas ki rele dipeptidyl peptidase IV inhibiteurs.STG te apwouve pa FDA an 2006.