4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Pite> 98.5% (HPLC) Lenvatinib Mesylate Faktori Entèmedyè
Ruifu Chimik Pwovizyon pou Lenvatinib Mesylate Entèmedyè ak Pite segondè
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Non Chimik | 4-Chloro-7-Methoxyquinoline-6-Carboxamide |
Sinonim | 4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Lenvatinib enpurte 12;Lenvatinib enpurite B;Lenvatinib enpurite LFS-B |
Nimewo CAS | 417721-36-9 |
Nimewo CAT | RF-PI1971 |
Estati Stock | Nan Stock, Kapasite Pwodiksyon 50MT / Ane |
Fòmil molekilè | C11H9ClN2O2 |
Pwa molekilè | 236.65 |
Pwen k ap fonn | > 205 ℃ (desanm) |
Dansite | 1.380±0.060 g/cm3 |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Off-blan pou limyè jòn poud |
Pite / Metòd analiz | >98.5% (HPLC) |
Pèt sou siye | <0.50% |
Rezid sou ignisyon | <0.50% |
Enpurte total | <1.50% |
Spectre proton RMN | Konfòm ak estrikti |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè nan Lenvatinib Mesylate (CAS: 857890-39-2) |
Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite
4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) se sitou itilize kòm yon entèmedyè nan Lenvatinib Mesylate (CAS: 857890-39-2).Devlope pa Eisai Inc., lenvatinib mesylate se yon inibitè reseptè faktè kwasans endothelial vaskilè (VEGF) ki gen aktivite kont VEGF subtip 1, 2, ak 3 e li te apwouve pa FDA an 2015 pou tretman kansè tiwoyid diferansye ki swa lokalman. frekan, metastatik, oswa pwogresif epi li pa t reponn ak tretman yòd radyo-aktif.Nan mwa me 2016, FDA te apwouve dwòg la kòm yon terapi konbinezon ak everolimus pou tretman kansè nan selil ren avanse.Paske VEGF (ak reseptè faktè kwasans fibroblast, ke yo rekonèt kòm FGFRs) yo panse yo jwe yon wòl nan chemen siyal kadyovaskilè, VEGF2R ak FGFR anpèchman yo panse yo dwe mekanis yo dèyè efè segondè prensipal lenvatinib mesylate, ki se tansyon wo.