Lapatinib Entèmedyè CAS 231278-84-5 Pite > 98.0% (HPLC)
Non Chimik | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Sinonim | Lapatinib Entèmedyè 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Nimewo CAS | 231278-84-5 |
Estati Stock | Nan Stock, Pwodiksyon Echèl Jiska Tòn |
Fòmil molekilè | C26H17ClFN3O3 |
Pwa molekilè | 473,90 |
Pwen k ap fonn | 225.0 a 235.0 ℃ |
Dansite | 1.407±0.06 g/cm3 |
Endèks refraktif | 1.694 |
COA & MSDS | Disponib |
Orijin | Shanghai, Lachin |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Pale jòn poud jòn jòn solid |
Pite / Metòd analiz | >98.0% (HPLC) |
Pwen k ap fonn | 225.0 ~ 235.0 ℃ |
Pèt sou siye | <1.00% |
Rezid sou ignisyon | <0.50% |
Enpurte total | <2.00% |
Metal lou (tankou Pb) | <20ppm |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè API (CAS 388082-77-7) |
Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite
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5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) se yon entèmedyè API (CAS 388082-77-7). ).(CAS 388082-77-7) se yon dwòg ki vize kansè nan tete devlope pa Britanik GlaxoSmithKline Co. Li se yon inibitè tirozin kinaz ki ka efektivman anpeche aktivite tirozin kinaz nan reseptè faktè kwasans epidèm imen 1 ak 2 (ErbB1, ErbB2).Li ka inikman aji nan yon varyete fason, asire ke selil kansè nan tete pa ka resevwa siyal kwasans.Li anpeche sit ATP intraselilè EGFR (ErbB-1) ak HER2 (ErbB-2), anpeche fosforilasyon selil timè ak aktivasyon, bloke siyal règleman desann atravè omojèn ak etewojenite EGFR (ErbB-1) ak HER2 (ErbB-1). dimerizasyon.
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