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Ibrutinib Entèmedyè CAS 330792-70-6 Pite> 98.0% (HPLC) Imaj Prezantasyon
  • Ibrutinib Entèmedyè CAS 330792-70-6 Pite > 98.0% (HPLC)

Ibrutinib Entèmedyè CAS 330792-70-6 Pite > 98.0% (HPLC)

Deskripsyon kout:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Pite:> 98.0% (HPLC)

Aparans: Off-White pou limyè jòn poud

Entèmedyè Ibrutinib (CAS: 936563-96-1) 

Kontakte: Dr Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Entèmedyè nan Ibrutinib:

Ibrutinib CAS 936563-96-1
3-Idroksipiperidin CAS 6859-99-0
1-Boc-3-Idroksipiperidin CAS 85275-45-2
(S)-1-Boc-3-Idroksipiperidin CAS 143900-44-1
4-Phenoxybenzoic asid CAS 2215-77-2
4-Phenoxyphenylboronic asid CAS 51067-38-0
4-Aminopyrazolo [3,4-d] pirimidin CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pirimidin CAS 151266-23-8
Ibrutinib Deacryloylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Pwopriyete chimik:

Non Chimik 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Sinonim Ibrutinib Entèmedyè N-3;3-Amino-5-(4-Phenoxyphenyl)pirazol-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pirazol;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Nimewo CAS 330792-70-6
Estati Stock Nan Stock, Pwodiksyon Echèl Jiska Tòn
Fòmil molekilè C16H12N4O
Pwa molekilè 276.29
Dansite 1.37±0.10 g/cm3
COA & MSDS Disponib
Orijin Shanghai, Lachin
Mak Ruifu Chimik

Espesifikasyon:

Atik Espesifikasyon
Aparans Off-blan pou limyè jòn poud
Pite / Metòd analiz >98.0% (HPLC)
Pèt sou siye <1.00%
Rezid sou ignisyon <0.50%
Enpurte total <2.00%
Metal lou (tankou Pb) <20ppm
Spectre 1H RMN Konfòm ak Estrikti
Tès Creole Enterprise Standard
Itilizasyon Entèmedyè Ibrutinib (CAS: 936563-96-1)

Pake & Depo:

Pake: Boutèy, sache papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an.

Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite.

Avantaj:

1

FAQ:

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330792-70-6 - Aplikasyon:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) se yon entèmedyè nan Ibrutinib (CAS: 936563-96-1).Ibrutinib montre efè inhibitor ki pisan ak irevokabl ak selektivite pou aktivite anzimatik Btk.Nan liy selil BCR aktive DOHH2, Ibrutinib inibit otofosforilasyon Btk, fosforilasyon substra fizyolojik Btk PLCγ, ak fosforilasyon plis en kinaz, ERK ak IC50 nan 11 nM, 29 nM ak 13 nM, respektivman.Ibrutinib montre yon endiksyon sitotoksisite enpòtan ki depann de dòz la epi ki depann de tan nan selil lesemi lenfositik kwonik (CLL).Anplis de sa, Ibrutinib pwovoke lanmò selil depann sou deklanchman wout caspase ak antagonize kapasite nan selil CLL yo pwopagasyon apre siyal TLR.

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