CAS 361440-67-7 Pite> 98.5% (HPLC) faktori
Entèmedyè ki gen rapò ak pwovizyon chimik Ruifu
CAS 361442-04-8
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Asid tert-Butyl Ester CAS 361440-67-7
2-(3-Idroksi-1-Adamantyl) -2-Oxoacetic Asid CAS 709031-28-7
Non Chimik | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Asid tert-Butyl Ester |
Sinonim | N-Boc-L-cis-4,5-Methanoprolineamid;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butil (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate |
Nimewo CAS | 361440-67-7 |
Nimewo CAT | RF-PI1990 |
Estati Stock | Nan Stock, Pwodiksyon Echèl Jiska Tòn |
Fòmil molekilè | C11H18N2O3 |
Pwa molekilè | 226.27 |
Pwen bouyi | 388.9±21.0℃ |
Dansite | 1.228 |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Poud blan |
Pite / Metòd analiz | >98.5% (HPLC) |
Pèt sou siye | <0.50% |
Rezid sou ignisyon | <0.20% |
Enpurte endividyèl yo | <1.00% |
Enpurte total | <1.50% |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè API (CAS: 361442-04-8) |
Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Asid tert-Butyl Ester (CAS: 361440-67-7) se yon entèmedyè nan API (CAS: 361442). -04-8).(CAS: 361442-04-8) se yon ipoglisemi oral (dwòg anti-dyabetik) nan klas inibitè dipeptidyl peptidase-4 (DPP-4) dwòg.Devlopman bonè se sèlman pa Bristol-Myers Squibb;an 2007 AstraZeneca ansanm ak Bristol-Myers Squibb pou ko-devlope konpoze final la ak kolabore sou maketing dwòg la.Nan mwa jen 2008, li te anonse ke Onglyza ta dwe non komèsyal anba ki pral commercialisés.API (CAS: 361442-04-8) yo itilize kòm monoterapi oswa an konbinezon ak lòt dwòg pou tretman dyabèt tip 2.Li absòbe rapidman apre administrasyon oral epi li gen yon pwofil farmakokinetik ki konpatib ak yon fwa chak jou.Li jwe wòl nan anpeche degradasyon GLP-l.GLP-I se òmòn yo pwodwi natirèlman nan trip la apre yo fin pran manje.