Lenvatinib Mesylate Entèmedyè CAS 205448-65-3 Pite > 98.0% (HPLC) Faktori
Ruifu Chimik Pwovizyon pou Lenvatinib Mesylate Entèmedyè ak Pite segondè
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Non Chimik | Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate |
Sinonim | 1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Asid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Asid Methyl Ester;Lenvatinib entèmedyè 3 |
Nimewo CAS | 205448-65-3 |
Nimewo CAT | RF-PI1973 |
Estati Stock | Nan Stock, Kapasite Pwodiksyon 50 MT / ane |
Fòmil molekilè | C12H11NO4 |
Pwa molekilè | 233.22 |
Pwen bouyi | 421.0±45.0℃ |
Dansite | 1.267±0.060 g/cm3 |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Off-blan a jòn poud |
Pite / Metòd analiz | >98.0% (HPLC) |
Pèt sou siye | <1.00% |
Rezid sou ignisyon | <0.50% |
Enpurte total | <2.00% |
H-NMR | Konfòm ak estrikti |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè famasetik |
Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) se yon entèmedyè nan Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, ki vann sou non mak Lenvima pami lòt moun, se yon medikaman anti-kansè pou tretman sèten kalite kansè tiwoyid ak pou lòt kansè tou.Li te devlope pa Eisai Co. epi li aji kòm yon inibitè kinaz miltip kont VEGFR1, VEGFR2 ak VEGFR3 kinaz yo.Lenvatinib apwouve (depi 2015) pou tretman kansè tiwoyid diferansye ki se swa lokalman frekan oswa metastatik, pwogresif, epi ki pa t reponn ak tretman ak yòd radyo-aktif (radyoyòd).Nan mwa me 2016, US Food and Drug Administration (FDA) te apwouve li (an konbinezon ak everolimus) pou tretman kansè selil ren avanse apre yon terapi anti-angiogenic anvan.Se dwòg la apwouve tou nan peyi Etazini ak nan Inyon Ewopeyen an pou kansè epatoselilè ki pa ka retire chirijikal nan pasyan ki pa te resevwa terapi kansè nan bouch oswa piki.