Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Pite > 98.0% (GC) Lenvatinib Mesylate Faktori Entèmedyè
Ruifu Chimik Pwovizyon pou Lenvatinib Mesylate Entèmedyè ak Pite segondè
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Non Chimik | Methyl 4-Amino-2-Methoxybenzoate |
Sinonim | 4-Amino-2-Methoxybenzoic Asid Methyl Ester;Methyl 4-Amino-o-Anisate;4-Amino-o-Anisic Asid Methyl Ester |
Nimewo CAS | 27492-84-8 |
Nimewo CAT | RF-PI1974 |
Estati Stock | Nan Stock, Pwodiksyon Echèl Jiska Tòn |
Fòmil molekilè | C9H11NO3 |
Pwa molekilè | 181.19 |
Dansite | 1.179±0.060 g/cm3 |
Mak | Ruifu Chimik |
Atik | Espesifikasyon |
Aparans | Blan poud blan oswa kristal |
Pite / Metòd analiz | >98.0% (GC) |
Pite / Metòd analiz | 97.5 ~ 102.5 (titrasyon non akeuz) |
Pwen k ap fonn | 157.0 ~ 161.0 ℃ |
Pèt sou siye | <1.00% |
Enpurte total | <2.0% |
Enfrawouj Spectrum | Konfòm ak estrikti |
Spectre proton RMN | Konfòm ak estrikti |
Tès Creole | Enterprise Standard |
Itilizasyon | Entèmedyè nan Lenvatinib Mesylate (CAS: 857890-39-2) |
Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an
Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite
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Methyl 4-Amino-2-Methoxybenzoate (CAS: 27492-84-8) ka itilize kòm yon entèmedyè nan Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib se yon dwòg kansè tiwoyid devlope pa Eisai Corporation nan Japon (Kòd: E7080), ki fè pati inibitè a nan oral milti-reseptè tirozin kinaz (RTK) epi li ka anpeche aktivite a kinaz nan faktè a kwasans endothelial vaskilè (VEGF) Reseptè VEGFR1. FLT1), VEGFR2 (KDR), ak VEGFR3 (FLT4).Lenvatinib kapab tou anpeche patisipasyon lòt RTK nan anjyogenesis patolojik, kwasans timè, ak pwogresyon kansè eksepte pou fonksyon selilè nòmal yo ki gen ladan reseptè FGFR1, 2, 3, ak 4 fibroblast kwasans faktè (FGF);reseptè faktè kwasans ki sòti nan plakèt (PDGFR [alfa]), KIT, ak RET.[Endikasyon]: Lenvatinib se apwopriye pou tretman pasyan kansè tiwoyid nan repetisyon lokal oswa kalite metastaz, kalite pwogresivite ak yòd radyoaktif-refractory kalite différenciés.Nan dat 13 fevriye 2015, US FDA te apwouve Lenvatinib dwòg antikansè pou tretman kansè tiwoyid.Lenvatinib se yon inibitè anzim milti-sib, ki kapab anpeche VEGFR2 ak VEGFR3 (reseptè faktè kwasans endothelial vaskilè).Non komèsyal Lenvatinib se Lenvima.Nan dat 20 me 2015, Ajans Medikaman Ewopeyen an (EMA) te apwouve Lenvatinib pou tretman kansè tiwoyid pwogrese, lokalman avanse oswa metastatik diferansye (papilè, folikulèr, kalite Hurthle) kansè tiwoyid (DTC).Nan jijman an, tan siviv medyàn pou pasyan ki gen DTC radyoaktif yòd-refractory trete ak Lenvatinib te 18 mwa pandan ke valè a pou pasyan ki pran plasebo se sèlman 3 mwa.
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Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8...
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Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~...
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Desquinolinyl Lenvatinib CAS 796848-79-8 Pite...
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4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatini...
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4-Amino-3-Chlorophenol Hydrochloride CAS 52671-...
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4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 4...
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Lenvatinib Mesylate Entèmedyè CAS 15568-85-1...
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Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylat...
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Lenvatinib Mesylate Entèmedyè CAS 205448-65-...