N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Pite> 99.0% (HPLC) Afatinib Dimaleate Entèmedyè Faktori En Imaj

N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Pite> 99.0% (HPLC) Afatinib Dimaleate Faktori Entèmedyè

Deskripsyon kout:

Non chimik: N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine

CAS: 162012-67-1

Pite:> 99.0% (HPLC)

Aparans: Limyè jòn poud jòn

Entèmedyè nan Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Deskripsyon:

Ruifu Chimik Pwovizyon pou Entèmedyè nan Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Asid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Asid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-yon sèl CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Pwopriyete chimik:

Non Chimik	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine
Sinonim	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitro-4-Quinazolinamine;(3-Chloro-4-Fluorophenyl) (7-Fluoro-6-Nitroquinazolin-4-yl) amine;4-(3-Chloro-4-Fluoroanilino) -7-Fluoro-6-Nitroquinazoline;Afatinib entèmedyè A
Nimewo CAS	162012-67-1
Nimewo CAT	RF-PI2026
Estati Stock	Nan Stock, Pwodiksyon Echèl Jiska Tòn
Fòmil molekilè	C14H7ClF2N4O2
Pwa molekilè	336,68
Sansiblite	Lè sansib, chalè sansib
Pwen k ap fonn	242.0 ~ 244.0 ℃
Pwen bouyi	489℃
Dansite	1.616
Mak	Ruifu Chimik

Espesifikasyon:

Atik	Espesifikasyon
Aparans	Limyè jòn poud jòn
Pite / Metòd analiz	>99.0% (HPLC)
Pèt sou siye	<0.50%
Rezid sou ignisyon	<0.20%
Sibstans ki gen rapò
Enpurte endividyèl	<0.50%
Enpurte total	<1.00%
Metal lou	≤20ppm
Enfrawouj Spectrum	Konfòm ak estrikti
Spectre proton RMN	Konfòm ak estrikti
Tès Creole	Enterprise Standard
Itilizasyon	Entèmedyè nan Afatinib Dimaleate (CAS: 850140-73-7)

Pake & Depo:

Pake: Boutèy, sak papye aliminyòm, 25kg / tanbou katon, oswa selon kondisyon kliyan an

Kondisyon Depo:Sere nan resipyan ki fèmen nan yon kote ki fre ak sèk;Pwoteje kont limyè ak imidite

Avantaj:

FAQ:

Aplikasyon:

N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine (CAS: 162012-67-1) se yon entèmedyè nan sentèz Afatinib Dimaleate (CAS: 850140-73-7) .Afatinib Dimaleate se yon fòm sèl nan Afatinib.Afatinib se yon dezyèm jenerasyon, ki administre oralman, inibitè irevokabl nan fanmi ErbB nan tirozin kinaz.Mekanis aksyon Afatinib downregulates ErbB siyal pa kovalans obligatwa nan domèn kinaz nan reseptè faktè kwasans epidèm (EGFR), reseptè faktè kwasans epidèm imen (HER) 2 ak HER4, sa ki lakòz irevokabl anpèchman nan otofosforilasyon tirozin kinaz;li tou inibit transfosforilasyon nan HER3.Afatinib apwouve kòm monoterapi pou tretman EGFR tyrosine kinase inhibitor (TKI) - granmoun nayif ak lokalman avanse oswa DefinitionChEBI: Yon sèl maleate yo jwenn nan konbine afatinib ak de ekivalan molè nan asid maleik.Itilize pou tretman premye liy pasyan ki gen kansè nan poumon metastatik ki pa ti selil.