1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS 22224-41-5 Ịdị ọcha ≥99.0% Clofarabine Intermediate High Cleanity
Ihe ndị metụtara Clofarabine na-eweta azụmaahịa:
Clofarabine CAS: 123318-82-1
2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose CAS: 97614-43-2
β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS: 6974-32-9
1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS: 22224-41-5
2,6-Dichloropurine CAS: 5451-40-1
Aha Chemical | 1,3,5-Tri-O-benzoyl-D-Ribofuranose |
Nọmba CAS | 22224-41-5 |
Nọmba CAT | RF-PI223 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C26H22O8 |
Ibu molekụla | 462.45 |
Ebe Na-agbaze | 125.0-129.0 ℃ (ọkụ) |
Solubility | Na-adịghị edozi n'ime mmiri |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ma ọ bụ Gbanyụọ-Ọcha ntụ ntụ |
Ịdị ọcha | ≥99.0% |
Ọnwụ na ihicha | ≤1.00% |
Oke adịghị ọcha otu | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.00% |
Ọla dị arọ | ≤20ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Clofarabine (CAS: 123318-82-1) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.
1,3,5-Tri-O-benzoyl-D-Ribofuranose (CAS: 22224-41-5) bụ ihe mmalite maka njikọ nucleoside.Enwere ike iji ya dịka etiti nke Clofarabine (CAS: 123318-82-1).Clofarabine bụ akwụkwọ akụkọ purine nucleoside ọgwụ anticancer bụ nke mbụ ụlọ ọrụ Top10 biopharmaceutical nke United States-Genzyme Corporation mepụtara nke ọma na aha azụmaahịa bụ “Clofarabine”.Na Disemba 28, 2004 FDA jiri usoro ngwa ngwa maka nkwado nke Clofarabine maka ngwa ụmụaka nwere ọrịa leukemia na-emegharị ma ọ bụ na-alaghachi azụ.Clofarabine jikọtara uru nke Fludarabine na Cladribine iji gbochie ma DNA polymerase na RIbonucleic acid reductase.Ugbu a ọ bụ naanị ọgwụ kwesịrị ekwesị maka ọgwụgwọ ọrịa leukemia nwata.Nnyocha egosiwo na arụmọrụ ọgwụgwọ ya dị oke elu, yana ọnụ ọgụgụ nzaghachi nke ndị ọrịa na-enweghị nzaghachi na chemotherapy abụọ bụ 31%.Na ndidi ndidi dị mma, ọ dịghị unpredictable oghom mmeghachi omume;Ọ nwere ikike antitumor nwere ike sara mbara.