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(1S,2S,3R,5S)-(+) -2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Ịdị ọcha ≥99.0% Bortezomib Intermediate High Cleanity Featured Image
  • (1S,2S,3R,5S)-(+) -2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Ịdị ọcha ≥99.0% Bortezomib Intermediate High-dị ọcha

(1S,2S,3R,5S)-(+) -2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Ịdị ọcha ≥99.0% Bortezomib Intermediate High-dị ọcha

Nkọwa dị mkpirikpi:

Aha kemịkal: (1S,2S,3R,5S)-(+)-2,3-Pinadiol

OZI: 18680-27-8

Ọdịdị: Ọcha ka Gbanyụọ-Ọcha Crystallized ntụ ntụ

ee: ≥99.0%Ịdị ọcha: ≥99.0% (GC)

Intermediate nke Bortezomib (CAS 179324-69-7) na ọgwụgwọ nke Multiple Myeloma

Ngwakọta Chiral, Mmepụta Azụmahịa

E-mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Nyefee Bortezomib njikọ etiti nwere ịdị ọcha dị elu
(1S,2S,3R,5S)-(+)-2,3-Pinadiol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7

Njirimara kemịkalụ:

Aha Chemical (1S,2S,3R,5S)-(+)-2,3-Pinadiol
Ụdị okwu (1S,2S,3R,5S) -2,6,6-Trimethylbicyclo[3.1.1] heptane-2,3-diol.
Nọmba CAS 18680-27-8
Nọmba CAT RF-CC290
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C10H18O2
Ibu molekụla 170.25
Solubility Chloroform, Toluene
Ọnọdụ mbupu Ebugara n'okpuru okpomọkụ gburugburu
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ụtụ ntụ ntụ na-acha ọcha ruo na-acha ọcha
Ebe Na-agbaze 56.0 ~ 59.0 ℃
Ọnwụ na ihicha ≤0.50%
Ihe fọdụrụ na mgbanye ≤0.50%
Enantiomeric ngafe ee ≥99.0%
Ụzọ ịdị ọcha / nyocha ≥99.0% (GC)
Ntụgharị a kapịrị ọnụ [α]20/D +8.5° ruo +9.5° (C=6.5, Toluene)
Spectrum infrared Dabara
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ngwakọta Chiral;Ndị n'etiti ọgwụ;Bortezomib Intermediate

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

1

Ajụjụ:

Ngwa:

Shanghai Ruifu Chemical Co., Ltd. bụ ndị na-eduga emeputa na soplaya nke (1S,2S,3R,5S)-(+) -2,3-Pinanediol (CAS 18680-27-8) na elu àgwà, ọtụtụ-eji organic. njikọ, njikọ nke pharmaceutical intermediates na ezi chemical njikọ.
Shanghai Ruifu Chemical Co., Ltd. na-arụ ọrụ dị mkpa na chemistry chiral, ụlọ ọrụ ahụ na-agba mbọ na mmepụta nke ogige chiral.Ndị ahịa na-eto ngwaahịa anyị n'ọtụtụ ebe.

(1S,2S,3R,5S)-(+) -2,3-Pinanediol (CAS 18680-27-8), bụ ihe bara uru Chiral reagent eji na njikọ nke homochiral α-hydroxyketones na mkpebi nke prolineboronate esters.Ọ bụkwa ihe mmalite bara uru maka chiral allyl boronate ejiri mee nkwadebe nke chiral β-hydroxyallylsilanes.

(1S,2S,3R,5S)-(+) -2,3-Pinanediol (CAS 18680-27-8) bụ Intermediate nke Bortezomib (CAS 179324-69-7) na ọgwụgwọ nke Multiple Myeloma.Bortezomib, onye na-egbochi ubiquitin proteasome (26S) (Ki = 0.6 nM), malitere na US dịka ọgwụgwọ maka otutu myeloma.A chọrọ proteasome a maka mmebi proteolytic nke ọtụtụ protein cellular ma dị na sel niile.Achọrọ ya maka njikwa nke usoro mkpali, usoro okirikiri cell na okwu mkpụrụ ndụ ihe nketa na bụ ebumnuche ọhụrụ na ọgwụgwọ ọrịa kansa.

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