2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Ịdị Ọcha>99.5% (HPLC) Tipiracil Hydrochloride Factory Intermediate Factory
Nbunye onye nrụpụta, Ogo dị elu na ọnụ ahịa asọmpi
Tipiracil Hydrochloride (CAS: 183204-72-0) Ndị na-emekọrịta ihe
6-(Chloromethyl) uracil CAS: 18592-13-7
6-(Hydroxymethyl) uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
Aha Chemical | 2-Amino-1-Pyrroline Hydrochloride |
Ụdị okwu | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
Nọmba CAS | 7544-75-4 |
Nọmba CAT | RF-PI1838 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C4H8N2·HCl |
Ibu molekụla | 120.58 |
Ebe Na-agbaze | 171.0 ka 175.0 ℃ |
Mmetụta | Hygroscopic |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta | Nsonaazụ |
Ọdịdị | Ọcha ntụ ntụ | Ọcha ntụ ntụ |
Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC) | 99.8% |
Kachasị adịghị ọcha otu | <0.50% | 0.09% |
Ọdịnaya Mmiri (KF) | <0.50% | 0.45% |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị | Dabara |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ | |
Ojiji | Ọkara nke Tipiracil Hydrochloride (CAS: 183204-72-0) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
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2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) bụ heterocyclic organic compound, nke a pụrụ iji dị ka onye na-emepụta ọgwụ na-eme ihe.2-Amino-1-Pyrroline Hydrochloride bụ n'etiti Tipiracil Hydrochloride (CAS: 183204-72-0) na ọgwụgwọ nke Rectal Cancer.Tipiracil Hydrochloride bụ onye na-egbochi ike na asọmpi nke thymidine phosphorylase (TPase) nwere uru IC50 nke 35 nM maka TPase placental mmadụ.Ọ bụ nhọrọ maka TPase karịa pyrimidine-metabolizing enzymes (IC50s => 1 mM maka UPase, OPRTase, TK, na DPDase).TPI na-egbochi phosphorolysis na mmebi nke trifluorothymidine, cytotoxic nucleoside, na ara mmadụ na colon carcinoma tumor sample.Nlekọta ọnụ nke TPI (12.5-50 mg / kg) na-akwalite ọrụ mgbochi tumor nke trifluorothymidine n'ụdị òké AZ-521 ọrịa cancer afọ xenograft.Ejirila usoro nwere TPI maka ọgwụgwọ ọrịa cancer colorectal metastatic.