2-Chloro-5-Iodobenzoic Acid CAS 19094-56-5 Empagliflozin Intermediate Assay ≥99.0% (HPLC)
Onye na-emepụta ihe, ịdị ọcha dị elu, mmepụta azụmahịa
Aha Chemical: 2-Chloro-5-Iodobenzoic Acid
OZI: 19094-56-5
Aha Chemical | 2-Chloro-5-Iodobenzoic acid |
Nọmba CAS | 19094-56-5 |
Nọmba CAT | RF-PI438 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C7H4ClIO2 |
Ibu molekụla | 282.46 |
Solubility | Soluble na methanol |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | kristal na-acha ọcha ma ọ bụ na-acha odo odo |
Usoro nyocha / nyocha | ≥99.0% (HPLC) |
Ebe Na-agbaze | 161.0 ~ 163.0 ℃ |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Mgbakọta adịghị ọcha | ≤1.0% |
Ọla dị arọ | ≤20ppm |
Ihe mgbaze fọdụrụnụ | Ethanol |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Empagliflozin (CAS: 864070-44-0) |
2-Chloro-5-Iodobenzoic Acid (CAS 19094-56-5) Ụzọ sịntetik
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Enwere ike iji 2-Chloro-5-Iodobenzoic Acid (CAS: 19094-56-5) dị ka onye na-ahụ maka ọgwụ na njikọ nke Empagliflozin (CAS: 864070-44-0).Empagliflozin (aha ahia Jardiance) bụ onye na-egbochi sodium glucose co-transporter-2 (SGLT-2), na-eme ka akụrụ wepụta shuga dị n'ọbara wee wepụ ya na mmamịrị.Na August 1, 2014, nri na ọgwụ nchịkwa (FDA) kwadoro ọgwụ ahụ maka ọgwụgwọ ụdị ọrịa shuga 2, iji melite na ịchịkwa glucose ọbara nke ndị okenye.Empagliflozin bụ ọgwụ SGLT-2 nke atọ na-egbochi ọgwụ FDA kwadoro.Ọgwụ abụọ SGLT-2 inhibitor, Canagliflozin na Dapagliflozin, nke Johnson Pharmaceuticals, AstraZeneca na Bristol-Myers Squibb n'otu n'otu, bụ ndị FDA kwadoro na Nọvemba 2013 na Jenụwarị 2014 n'otu n'otu.
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