2- (Chloromethyl) -4-Methylquinazoline CAS 109113-72-6 Linagliptin Intermediate Purity ≥99.0% (HPLC)

Nkọwa dị mkpirikpi:

Aha Chemical: 2-(Chloromethyl) -4-Methylquinazoline

Ọkụ: 109113-72-6

Dị ọcha: ≥99.0% (HPLC)

Ọdịdị: Acha odo odo na-acha uhie uhie na ntụ ntụ

Nke etiti maka Linagliptin (CAS: 668270-12-0) maka ọgwụgwọ ndị okenye nwere ụdị ọrịa shuga 2.

Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Onye nrụpụta Linagliptin na ihe ndị metụtara ya:
Linagliptin CAS 668270-12-0
Nne na nna Linagliptin Nucleus Intermediate CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7- (2-butyn-1-yl) -3-methylxanthine CAS 666816-98-4
2- (Chloromethyl) -4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino) piperidine CAS 309956-78-3
(R)-(-)-3-Aminopperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0

Njirimara kemịkalụ:

Aha Chemical	2- (Chloromethyl) -4-Methylquinazoline
Ụdị okwu	Linagliptin Intermediate A
Nọmba CAS	109113-72-6
Nọmba CAT	RF-PI498
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C10H9ClN2
Ibu molekụla	192.64
Njupụta	1.251
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Icha odo odo ka ọ bụrụ ntụ ntụ ntụ ntụ
njirimara A	Ụdị ụdịdị dị iche iche nke IR ga-adabarịrị na ọkọlọtọ ọkọlọtọ
njirimara B	Oge njide nke ụkpụrụ kacha elu nke ihe nlele ga-adabarịrị na ọkọlọtọ
Solubility	Soluble na Methylene chloride;Na-adịghị edozi n'ime mmiri
Ụzọ ịdị ọcha / nyocha	≥99.0% (HPLC)
Ebe Na-agbaze	60.0 ruo 65.0 ℃
Mmiri (KF)	≤0.50%
Ihe fọdụrụ na mgbanye	≤0.50%
Ihe ndị emetụtara
Otu adịghị ọcha	≤0.30%
Mgbakọta adịghị ọcha	≤1.0%
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara maka Linagliptin (CAS: 668270-12-0)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

Ajụjụ:

Ngwa:

2- (Chloromethyl) -4-Methylquinazoline (CAS: 109113-72-6) ka a na-eji dị ka etiti maka nkwadebe nke Linagliptin (CAS: 668270-12-0), na adịghị ọcha ya.Linagliptin, nke a na-ere n'okpuru akara aha Tradjenta n'etiti ndị ọzọ, bụ ọgwụ a na-eji agwọ ọrịa shuga mellitus ụdị 2. Ọ na-adịkarị mma karịa metformin na sulfonylureas dị ka ọgwụgwọ mbụ.A na-eji ya na mgbatị ahụ na nri.A naghị atụ aro ya na ụdị ọrịa shuga 1.Ọ na-arụ ọrụ site na ịbawanye mmepụta insulin na ibelata mmepụta glucagon site na pancreas.A kwadoro Linagliptin maka iji ahụike na United States na 2011. Linagliptin bụ ihe na-eme ka ọ dị ike nke ukwuu, onye na-emechi dipeptidyl peptidase-4 (DPP-4) nwere IC50 nke 1 nM.