2-Methyltryptamine CAS 2731-06-8 Dị Ọcha>99.0% (HPLC) Panobinostat Intermediate Factory High Quality
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Aha ọgwụ: 2-Methyltryptamine CAS: 2731-06-8
Aha Chemical | 2-Methyltryptamine |
Ụdị okwu | 2-Methylindole-3-Ethylamine;2- (2-Methyl-1H-indol-3-yl) etanamine;3- (2-Aminoethyl) -2-Methylindole |
Nọmba CAS | 2731-06-8 |
Nọmba CAT | RF-PI1480 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C11H14N2 |
Ibu molekụla | 174.25 |
Ebe Na-agbaze | 106.0 ka 110.0 ℃ |
Ebe esi nri | 177 ℃/1.5mmHg (ọkụ) |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Brown siri ike |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC Mpaghara) |
1-HNMR | Nkwekọrịta na Ọdịdị |
Ọnwụ na ihicha | <1.00% |
Otu adịghị ọcha | <0.50% |
Mgbakọta adịghị ọcha | <1.00% |
Ọla dị arọ (dị ka Pb) | <20ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ndị n'etiti ọgwụ;Panobinostat Intermediate |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
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2-Methyltryptamine (CAS: 2731-06-8) bụ isi mmalite ihe na njikọ nke Panobinostat (LBH589) (CAS: 404950-80-7).Panobinostat bụ ihe mgbochi siri ike nke histone deacetylases (HDACs), yana ụkpụrụ Ki sitere na 0.6 ruo 31 nM maka HDAC1-11.Site na omume a, ọ na-eduga na acetylation nke ọtụtụ protein cellular, na-ebute njide okirikiri cell na apoptosis na mkpụrụ ndụ kansa.Panobinostat bụ onye mbụ na-egbochi HDAC nke FDA kwadoro maka ọgwụgwọ nke otutu myeloma.A na-ere ahịa Panobinostat dị ka Farydak, ejiri ya na Bortezomib (CAS: 179324-69-7) na Dexamethasone (CAS: 50-02-2) iji gwọọ ọtụtụ myeloma azụghachi azụ mgbe ọgwụgwọ mbụ na Bortezomib na immunomodulator gasịrị.
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