2′,3′-Di-O-acetyl-5′-deoxy-5-fluorocytidine CAS 161599-46-8 Ịdị ọcha ≥99.0% Capecitabine Intermediate Factory
Mgbakwunye Capecitabine metụtara azụmahịa:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
Aha | 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine |
Nọmba CAS | 161599-46-8 |
Nọmba CAT | RF-PI176 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C13H16FN3O6 |
Ibu molekụla | 329.28 |
Ọnọdụ Ịzere | Okpomọkụ nwere mmetụta |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Crystalline ntụ ntụ na-acha ọcha ma ọ bụ odo odo |
Otu adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Ebe Na-agbaze | 178.0-193.0 ℃ |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Mmiri (KF) | ≤1.0% |
Nyocha | ≥99.0% |
Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Nke etiti Capecitabine (CAS: 154361-50-9) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.
Capecitabine (CAS: 154361-50-9) bụ ụdị ọhụrụ nke ọgwụ pyrimidine nwere fluorinated.Roche Pharmaceuticals mepụtara Capecitabine, aha azụmahịa ya bụ Xeloda.Capecitabine nwere ike gbanwee na vivo n'ime 5-FU, ọgwụ anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate ọgwụ nke na-elekwasị anya na mkpụrụ ndụ kansa iji gbochie nkewa sel ma mebie RNA na njikọ protein.A na-ejikọta mmetụta ya na ọkwa nke TP enzyme okwu na anụ ahụ neoplastic na DPD enzyme na vivo okwu.Ọ dabara nke ọma dị ka ọgwụgwọ ọzọ maka ndị ọrịa kansa ara nke mbụ ma ọ bụ metastatic bụ ndị na-anabataghị ọgwụ nje paclitaxel ma ọ bụ anthracycline.Dị ka ọgwụ mgbochi ọrịa cancer, a na-ejikarị agwọ ọrịa kansa ara ma ọ bụ metastatic dị elu, yana ọgwụgwọ maka ọrịa cancer akpa ume na-abụghị obere cell, cancer pancreatic, cancer eriri afo, cancer rectal, colon cancer, gastric cancer, na ndị ọzọ siri ike etuto ahụ. .