2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Intermediate Dị Ọcha>99.0% (GC)

2,3-Dihydrobenzofuran (CAS: 496-16-2) na-ejikarị eme ihe na njikọ nke ogige tricyclic ma bụrụkwa ihe dị n'etiti maka njikọ nke ọgwụ ụfọdụ dị mkpa.Enwere ike iji 2,3-Dihydrobenzofuran mee ihe dị ka etiti nke Ramelteon (CAS: 196597-26-9).Ramelteon, nke a na-erere dị ka Rozerem site na Takeda Pharmaceuticals North America, bụ onye na-ehi ụra nke na-ahọrọ ndị na-anabata MT1 na MT2 na suprachiasmatic nucleus (SCN), kama ijikọta ndị na-anabata GABAA, dị ka ọgwụ dị ka zolpidem.Otú ọ dị, ọ pụtaghị na ọ na-eme ka ihi ụra malite ngwa ngwa ma ọ bụ ụra ole mmadụ na-ehi.Ndị nchịkwa nri na ọgwụ ọjọọ nke US (FDA) kwadoro ya maka iji ogologo oge.Ramelteon anaghị egosi njikọ ọ bụla nwere ekele maka ndị na-anabata GABAA, nke jikọtara ya na mmetụta anxiolytic, myorelaxant na amnesic.N'adịghị ka ọtụtụ ọgwụgwọ nke ehighị ụra nke ọma na-elekwasị anya na GABA (g-aminobutyric acid), ramelteon bụ agonist nke melatonin receptor.Karịsịa, ọ nwere nhọrọ dị elu maka ụdị subtypes MT1 na MT2, bụ ndị etinyere aka na mmezi nke usoro okirikiri circadian, n'elu onye na-anabata MT3 na-ahụ maka ọrụ melatonin ndị ọzọ.2,3-Dihydrobenzofuran na-ejikwa ya na njikọ nke antitumor agents benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, wdg.