2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Intermediate COVID-19

Nkọwa dị mkpirikpi:

Aha: 2,3,5-Tri-O-benzyl-D-ribonolactone

Okwu ndị yiri: 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone

Ọnọdụ: 55094-52-5

Ọdịdị: Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha ntụ ntụ

ịdị ọcha: ≥99.0%

Ọkara nke Remdesivir (CAS 1809249-37-3) COVID-19

Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Onye nrụpụta Azụmahịa Remdesivir na ihe ndị metụtara ya nwere ogo dị elu
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S) -2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Metabolite Remdesivir (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Intermediate CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Njirimara kemịkalụ:

Aha Chemical	2,3,5-Tri-O-benzyl-D-ribonolactone
Ụdị okwu	2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Intermediate
Nọmba CAS	55094-52-5
Nọmba CAT	RF-PI301
Ọnọdụ Ahịa	Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi	C26H26O5
Ibu molekụla	418.49
Ebe Na-agbaze	54.0-55.0 ℃
Ọnọdụ Nchekwa	Okpomọkụ ụlọ
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Yellowish ma ọ bụ White siri ike
Solubility	Soluble na CH2Cl2 na enweghị ike soluble na H2O
NMR na MS	Kwesịrị ịgbaso
njirimara	IR na TLC
Mmiri	≤1.0%
Ihe fọdụrụ na mgbanye	≤0.50%
Ọdịghị ọcha nke Onye ọ bụla	≤0.50%
Ọla dị arọ	≤50ppm
HPLC (210nm)	≥99.0%
HPLC (ELSD)	≥99.0%
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara nke Remdesivir (CAS 1809249-37-3)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) bụ etiti Remdesivir.Remdesivir (CAS 1809249-37-3) bụ ọgwụ mgbochi ọhụụ na klas nke nucleotide analọg, ejiri na ọgwụgwọ COVID-19.Remdesivir (GS-5734) bụ akwụkwọ akụkọ antiviral nucleoside analogue nke na-egbochi nje ịba ọcha n'anya murine (MHV) nwere EC50 yiri SARS-CoV na MERS-CoV.Coronaviruses (CoVs) bụ ezi uche, nje virus RNA nwere otu eriri na-efe efe n'ọtụtụ anụmanụ.N'ime ụmụ mmadụ, a ghọtara CoV dị ka ọ na-ebutekarị oyi na oyi baa ruo mgbe mmalite nke nnukwu ọrịa iku ume iku ume coronavirus (SARS-CoV) na 2002 na Middle East respiratory syndrome coronavirus (MERS-CoV) na 2012 sitere na isi mmalite zoonotic.Remdesivir bụ monophosphoramidate prodrug nke C-adenosine nucleoside analogue GS-441524.N'ime mkpụrụ ndụ ụbụrụ ụbụrụ na-egbu oge (DBT) na-ebute ọrịa MHV, GS-5734 gbochiri MHV karịa GS-441524, na GS-5734 EC50 nke 0.03 M. Ọzọkwa, a na-ekpebi ụkpụrụ EC50 mgbe ọgwụgwọ na GS-441524 na GS-5734 N'ime omenala SARS-CoV- na MERS-CoV-ebutere mmadụ isi ikuku epithelial cell (HAE).