2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Ịdị Ọcha ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Intermediate
Nnweta Sitagliptin Phosphate Monohydrate Njikọta:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
| Aha Chemical | 2,4,5-Trifluorophenylacetic acid |
| Nọmba CAS | 209995-38-0 |
| Nọmba CAT | RF-PI1191 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C8H5F3O2 |
| Ibu molekụla | 190.12 |
| Ebe Na-agbaze | 121.0 ruo 125.0 ℃ |
| Solubility | Soluble na methanol |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
| Ụzọ ịdị ọcha / nyocha | ≥99.5% (GC) |
| Mmiri (KF) | ≤0.50% |
| Ihe fọdụrụ na Igniton | ≤0.50% |
| Mgbakọta adịghị ọcha | ≤0.50% |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) bụ etiti nke Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).A na-eji Sitagliptin Phosphate (STG) na-agwọ DM ụdị 2 n'ihi na ọ na-eme ka njikwa glycemic dịkwuo elu site na ịbawanye ọkwa nke homonụ incretin na-arụ ọrụ, GLP-1 (peptide-1) na GIP (glucose-based insulinotropic peptide).Ntinye nke incretins ndị a na sel β-pancreatic na-akpata mmụba nke cyclic adenosine monophosphate (cAMP) na calcium intracellular, yana ntinye insulin na-adabere na glucose na-esote (2).Ọgwụ hypoglycemic a bụ nke klaasị ọhụrụ akpọrọ dipeptidyl peptidase IV inhibitors.FDA kwadoro STG na 2006.
