(2S, 3S) -1,2-Epoxy-3- (Boc-Amino) -4-Phenylbutane CAS 98737-29-2 Darunavir Intermediate High Purity
Ngwaahịa ndị emetụtara Darunavir onye nrụpụta:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
Aha Chemical | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
Ụdị okwu | (2S, 3S) -3- (Boc-Amino) -1,2-Epoxy-4-Phenylbutane;(2S, 3S) -3- (tert-Butoxycarbonylamino) -1,2-epoxy-4-phenylbutane;Darunavir Intermediate |
Nọmba CAS | 98737-29-2 |
Nọmba CAT | RF-PI286 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C15H21NO3 |
Ibu molekụla | 263.33 |
Solubility | Na-adịghị edozi n'ime mmiri.Soluble na methanol, Chloroform |
Ọnọdụ mbupu | Ebugara n'okpuru okpomọkụ gburugburu |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
njirimara (HPLC) | HPLC kwadoro njirimara a |
Ebe Na-agbaze | 123.0 ~ 128.0 ℃ |
Mmiri (KF) | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) |
Chlorohydrin (HPLC) | ≤0.20% |
Chloromethyl ketone | ≤0.10% |
Ndị ọzọ Otu adịghị ọcha | ≤0.20% |
Mgbakọta adịghị ọcha | ≤1.0% |
Chiral adịghị ọcha | ≤0.30% |
Ọla dị arọ | ≤20ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ihe etiti nke Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata (2S,3S) -1,2-Epoxy-3- (Boc-Amino) -4-Phenylbutane (CAS: 98737-29-2) nwere oke mma. , nke etiti na-emekarị na njikọ nke Darunavir (CAS 206361-99-1) na Darunavir Ethanolate (CAS 635728-49-3).
Darunavir (CAS 206361-99-1) bụ ụdị ọhụrụ na-abụghị peptide mgbochi retroviral protease inhibitors na ọgwụgwọ AIDS.Nke izizi ya bụ alaka ụlọ ọrụ na-ahụ maka ọgwụ Johnson nke Iceland, Tibotec.Ọ bụ nke kachasị elu bioavailability na 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir na ABT378/r).Ọ na-eme ihe site n'igbochi irighiri nje virus ọhụrụ ma tozuru oke site n'elu sel ndị butere ọrịa na igbochi protease nke nje.Mgbe a na-eji ngwaahịa a ogologo oge, ọ na-enwekarị ike ibelata vector nje HIV n'ime ọbara, mee ka ọnụ ọgụgụ nke sel CD4 dịkwuo elu, belata ohere nke nje HIV, meziwanye ndụ ndụ na ogologo ndụ.Ọ dị mma maka ndị toro eto bu nje HIV mana enweghị mmetụta ọ bụla n'iji ọgwụ antiretroviral dị adị.A ghaghị ijikọta ọgwụ ahụ na iji obere doses nke ritonavir ma ọ bụ ihe ndị ọzọ na-egbochi ọrịa retroviral, iji mee ka ọ dị mma.