3-Ethynylaniline CAS 54060-30-9 Ịdị ọcha>99.0% (GC) Erlotinib Hydrochloride Intermediate
Onye na-emepụta ihe na onye na-ebubata Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-otu CAS 179688-29-0
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Aha Chemical | 3-Ethynylaniline |
Ụdị okwu | 3-Aminophenylacetylene |
Nọmba CAS | 54060-30-9 |
Nọmba CAT | RF-PI2241 |
Ọnọdụ Ahịa | Na Akụrụngwa, Ike nrụpụta 50MT / ọnwa |
Usoro ihe omimi | C8H7N |
Ibu molekụla | 117.15 |
Mmetụta | Mmetụta ikuku, Mmetụta ọkụ |
Ebe esi nri | 120 ℃/20 mmHg |
Mmiri Solubility | Na-adịghị edozi n'ime mmiri |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Icha odo odo gaa na mmiri mmiri Brown |
Ụzọ ịdị ọcha / nyocha | > 99.0% (GC) |
Mmiri nke Karl Fischer | <0.50% |
Ihe fọdụrụ na mgbanye | <0.20% |
Mgbakọta adịghị ọcha | <1.00% |
Nnukwu ike ndọda (20/20 ℃) | 1.041-1.048 |
Ntụgharị ntụgharị n20/D | 1.614-1.6195 |
Spectrum infrared | Dabara na Ọdịdị |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ndị na-emepụta ọgwụ na etiti;Erlotinib Hydrochloride Intermediate |
ngwugwu: Klas Fluorinated, 25kg/Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
3-Ethynylaniline, nke a makwaara dị ka 3-Aminophenylacetylene (CAS: 54060-30-9) na-eji dị ka onye na-ahụ maka ọgwụ.3-Ethynylaniline bụ etiti Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochloride bụ obere molecule tyrosine kinase inhibitor nke na-eme mgbanwe na ndị na-anabata uto epidermal, hydrochloride nke erlotinib, ọgwụ ezubere iche.Ndị nchịkwa nri na ọgwụ ọjọọ nke US (FDA) akwadoro erlotinib (Tarceva) yana gemcitabine dịka ọgwụgwọ mbụ maka ọrịa cancer pancreatic dị elu na mpaghara metastatic.A na-ejikarị ya dị ka ọgwụgwọ nke abụọ ma ọ bụ nke atọ maka ọrịa cancer akpa ume na mpaghara ma ọ bụ metstatic na-abụghị obere cell (NSCLC) yana dịka ọgwụgwọ maka ọrịa cancer pancreatic.A na-eji ya dị ka ihe mgbochi tyrosine maka ọgwụgwọ NSCLC.Erlotinib Hydrochloride, quinazoline ewepụtara obere molecule inhibitor nke epidermal growth receptor (EDGFR) tyrosine kinase, ka akwadoro na Nọvemba, 2004, maka ọgwụgwọ ọrịa cancer akpa ume dị elu ma ọ bụ metastatic na-abụghị obere mkpụrụ ndụ.