4-Benzyl-2-Hydroxymorpholin-3-otu CAS 287930-73-8 Ịdị Ọcha>99.0% (HPLC) Ụlọ Ọrụ Na-ahụ Maka Mgbochi Aprepitant
Ndị na-emepụta ihe na ndị na-ebubata ihe
Ndị etiti nke Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-otu CAS 287930-73-8
(R) -1-[3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com
| Aha Chemical | 4-Benzyl-2-Hydroxymorpholin-3-otu |
| Ụdị okwu | 4-Benzyl-2-Hydroxy-Morpholin-3-otu;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Ihe na-adịghị mma 48;Fosaprepitant adịghị ọcha 23;Ọkara etiti Ⅱ |
| Nọmba CAS | 287930-73-8 |
| Nọmba CAT | RF2660 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C11H13NO3 |
| Ibu molekụla | 207.23 |
| Ebe Na-agbaze | 134.0 ruo 138.0 ℃ |
| Ebe esi nri | 441.7± 45.0 ℃ |
| Njupụta | 1.292±0.06 g/cm3 |
| Solubility na Mmiri | DMSO (obere), methanol (obere, ọkụ) |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-acha ọcha |
| Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
| Ebe Na-agbaze | 134.0 ruo 138.0 ℃ |
| Mmiri (nke Karl Fischer) | <0.50% |
| Ihe fọdụrụ na mgbanye | <0.20% |
| Mgbakọta adịghị ọcha | <1.00% |
| Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Aprepitant (CAS: 170729-80-3) Ọgwụ mgbochi emetic |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Kedu ka esi azụta?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
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Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Russia, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
4-Benzyl-2-Hydroxymorpholin-3-otu (CAS: 287930-73-8), bụ etiti nke Aprepitant (CAS: 170729-80-3), eji dị ka ọgwụ antiemetic.Aprepitant bụ onye na-anabata neurokinin-1 (NK-1) ma bụrụkwa nke ndị na-agwọ ọgbụgbọ n'oge chemotherapy nke ọrịa kansa.Ụlọ ọrụ Merck (German) mepụtara ya nke ọma.Na Maachị 2003, nchịkwa nri na ọgwụ ọjọọ nke US kwadoro ya maka iji ya na ọgwụgwọ nke vomiting chemotherapy.Ngwaahịa a nwere oke nhọrọ nhọrọ na ụmụ mmadụ ebe ọ nwere njikọ dị ala na serotonin, dopamine na glucocorticoid receptor affinity.Aprepitant, mgbe ejikọtara ya na 5-HT3 receptor inhibitors (dị ka ondansetron hydrochloride) na corticosteroid dexamethasone, nwere ike ọzọ ibelata cisplatin na-ebute nnukwu na (ma ọ bụ) emesis na-egbu oge.Itinye ọgwụ a naanị nwere ike inwe mmetụta mgbochi ụfọdụ.
![(R) -1-[3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2 Ịdị ọcha> 99.0% (GC) Aprepitant Intermediate](https://www.ruifuchemical.com/uploads/R-1-35-Bistrifluoromethylphenylethanol-CAS-127852-28-2-300x300.jpg)